Avastin (bevacizumab)

DRUG15 trials

Sponsors

Genentech, Inc., M.D. Anderson Cancer Center, Shahid Beheshti University of Medical Sciences, London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's, Rigshospitalet, Denmark

Conditions

Age Related Macular DegenerationBreast CancerCancerCarcinoma, Non-Small-Cell LungColorectal CancerDiabetesDiabetes ComplicationsDiabetic Macular Edema

Phase 2

A Study Evaluating Tarceva in Combination With Avastin Versus Avastin Alone in Treating Metastatic Renal Cell Carcinoma

CompletedNCT00081614

Genentech, Inc.Metastases, Renal Cell Carcinoma

Start: 2004-03-31End: 2005-07-31Target: 100Updated: 2014-05-16

A Study to Evaluate Bevacizumab and Chemotherapy or Tarceva in Treating Recurrent or Refractory NSCLC (Non-Small Cell Lung Cancer)

CompletedNCT00095225

Genentech, Inc.Neoplasm Recurrence, Local, Non-Small-Cell Lung Carcinoma

Start: 2004-07-31End: 2006-11-30Updated: 2008-01-29

An Extension Study to Evaluate Avastin in Patients Treated in a Previous Genentech-Sponsored Cancer Study

CompletedNCT00109057

Genentech, Inc.Cancer

Start: 1998-02-28End: 2004-02-29Updated: 2013-06-21

A Study to Evaluate Avastin in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer

CompletedNCT00109226

Genentech, Inc.Colorectal Cancer

Start: 2000-08-31End: 2003-09-30Updated: 2014-04-08

Preop Chemoradiation Resectable Pancreas

CompletedNCT00336648

M.D. Anderson Cancer CenterPancreatic Neoplasms

Start: 2006-06-30End: 2008-07-31Updated: 2012-07-30

Combination Therapy for Age-Related Macular Degeneration.

CompletedNCT00376701

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sAge Related Macular Degeneration

Start: 2006-09-30End: 2009-04-30Updated: 2011-09-28

Cisplatin/Paclitaxel/Gemcitabine +/- Avastin in Patients With Unknown Primary Tumor

WithdrawnNCT00458315

Rigshospitalet, DenmarkUnknown Primary Tumors

Start: 2007-05-31End: 2012-05-31Updated: 2015-05-08

Efficacy of Neoadjuvant Chemoradiation for Potentially Resectable Pancreas Cancer

CompletedNCT00557492

Amer ZureikatPancreatic Cancer

Start: 2006-12-31End: 2016-12-31Updated: 2018-09-25

Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema

CompletedNCT01787669

University of SydneyDiabetes, Diabetic Macular Edema, Diabetic Macular Oedema +1

Start: 2013-06-30End: 2017-10-31Updated: 2018-11-13

Phase 3

A Study to Evaluate Avastin in Patients Treated in a Previous Genentech-Sponsored Cancer Study

CompletedNCT00096967

Genentech, Inc.Breast Cancer, Colorectal Cancer, Metastases

Start: 2002-10-31End: 2004-07-31Target: 100Updated: 2014-03-26

A Study to Evaluate Avastin in Combination With Standard Chemotherapy to Treat Colorectal Cancer

CompletedNCT00109070

Genentech, Inc.Colorectal Cancer

Start: 2000-09-30End: 2003-04-30Updated: 2013-06-21

Intravitreal Bevasizumab VS Sham Treatment in Acute BRVO: A Randomized Clinical Trial

CompletedNCT00370851

Shahid Beheshti University of Medical SciencesRetinal Disease

Start: 2006-08-31End: 2008-06-30Updated: 2009-11-25

Evaluation of FKB238 and Avastin in Patients With Advanced/Recurrent Non-squamous Non-small Cell Lung Cancer

CompletedNCT02810457

Centus Biotherapeutics LimitedCarcinoma, Non-Small-Cell Lung

Start: 2016-09-07End: 2022-01-26Updated: 2022-03-10

Unknown Phase

Avastin for PDR (Proliferative Diabetic Retinopathy)

CompletedNCT01270542

University of Southern CaliforniaDiabetic Retinopathy, Retinal Detachment

Start: 2009-06-30End: 2012-07-31Updated: 2017-08-17

Effect of Intravitreal Bevacizumab on Focal Edema With Hard Exudates Secondary to Diabetic Retinopathy

Seoul St. Mary's HospitalDiabetes Complications

Start: 2011-08-31End: 2012-02-29Target: 10Updated: 2011-09-23

Related Papers

Efficacy and Safety of Bevacizumab Biosimilar FKB238 Versus Originator Bevacizumab: Results from AVANA, a Phase III Trial in Patients with Non-Squamous Non-Small-Cell Lung Cancer (non-sq-NSCLC)

BioDrugs2021-07-0121 citations

Efficacy and safety of bevacizumab biosimilar FKB238 versus originator bevacizumab: Results from a phase III trial in patients with non-squamous non-small cell lung cancer (NS-NSCLC).

Journal of Clinical Oncology2020-05-202 citations

Efficacy outcomes with bevacizumab added to chemotherapy (bev+CT) compared with chemotherapy alone (CT) in left- and right-sided tumors in metastatic colorectal cancer (mCRC).

Journal of Clinical Oncology2018-02-015 citations

Sequential neoadjuvant chemoradiotherapy (CRT) followed by curative surgery vs. primary surgery alone for resectable, non-metastasized pancreatic adenocarcinoma: NEOPA- a randomized multicenter phase III study (NCT01900327, DRKS00003893, ISRCTN82191749)

BMC Cancer2014-06-0781 citations

Angiofibrotic response to vascular endothelial growth factor inhibition in diabetic retinal detachment: report no. 1.

2012-09-0139 citations