Amyvid

DRUG4 trials

Sponsors

Columbia University, Invicro, University of Southern California

Conditions

Alzheimer DiseaseAlzheimer Disease, Early OnsetDementiaMild Cognitive Impairment

Phase 1

Plasma P-tau2017 and Quantitative Amyloid PET Imaging

CompletedNCT05164536

InvicroAlzheimer Disease

Start: 2021-08-27End: 2022-11-08Updated: 2025-02-28

Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau

Not yet recruitingNCT06600880

Columbia UniversityAlzheimer Disease, Early Onset

Start: 2026-08-31End: 2027-12-31Target: 6Updated: 2025-05-11

Unknown Phase

Non-invasive Blood-brain Barrier Opening in Alzheimer's Disease Patients Using Focused Ultrasound

CompletedNCT04118764

Columbia UniversityAlzheimer Disease

Start: 2020-08-06End: 2022-09-28Updated: 2024-08-26

Alzheimer's Disease Neuroimaging Initiative 4

Enrolling by invitationNCT05617014

University of Southern CaliforniaAlzheimer Disease, Dementia, Mild Cognitive Impairment

Start: 2023-06-09End: 2027-07-31Target: 1500Updated: 2026-03-25

Related Papers

Blood–brain barrier opening of the default mode network in Alzheimer’s disease with magnetic resonance-guided focused ultrasound

Brain2023-01-2561 citations

Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients

Theranostics2023-01-0138 citations