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Aminocaproic acid

DRUG6 trials

Sponsors

Astrazeneca AB, Astrazeneca AB, Vanderbilt University, Loma Linda University, Grupo de Estudos Multicentricos em Onco-Hematologia, King Abdul Aziz Specialist Hospital

Conditions

Cardiopulmonary BypassFibrinolysisInflammationOpioid Pain MedicationOral HemorrhageReversal of anticoagulation effect in patients on a FXa inhibitor (apixabanSurgeryTraumatic Bleeding

Phase 2

Bradykinin Receptor Antagonism During Cardiopulmonary Bypass
CompletedNCT00223704
Vanderbilt UniversityCardiopulmonary Bypass, Fibrinolysis, Inflammation +1
Start: 2006-05-31End: 2012-06-30Updated: 2013-11-25

Phase 3

A Randomized Study of Andexanet Alfa Compared to Usual Care in Patients Receiving a Factor Xa Inhibitor who Require Urgent Surgery or Procedure (ANNEXA-RS)
CompletedCTIS2022-501353-37-00
Astrazeneca AB, Astrazeneca ABand who have a major risk of bleeding., or edoxaban) who require urgent surgery or procedure, Reversal of anticoagulation effect in patients on a FXa inhibitor (apixaban +1
End: 2024-06-13Target: 467Updated: 2024-02-19

Phase 4

Randomized Clinical Trial With Aminocaproic Acid in the Prevention of Exodontic Bleeding in Anticoagulants Patients
NCT02238288
Grupo de Estudos Multicentricos em Onco-HematologiaOral Hemorrhage
Start: 2013-12-31End: 2015-07-31Target: 154Updated: 2014-09-12
Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation
TerminatedNCT04814433
NYU Langone HealthOpioid Pain Medication
Start: 2021-03-24End: 2023-07-10Updated: 2024-06-26

Unknown Phase

Comparison of Tranexamic to Epsilon Aminocaproic Acid: a Prospective Analysis of Blood Conservation in Cardiac Surgery
CompletedNCT01248104
Loma Linda UniversityCardiopulmonary Bypass
Start: 2010-03-31End: 2015-02-28Updated: 2020-10-19
Activated Factor Seven in Traumatic Retro Peritoneal Hematoma
CompletedNCT04424563
King Abdul Aziz Specialist HospitalTraumatic Bleeding
Start: 2017-05-05End: 2019-12-30Updated: 2020-06-11