Allogeneic HSCT
Sponsors
Stanford University, Universitätsklinikum Hamburg-Eppendorf, PETHEMA Foundation, National Cancer Institute (NCI), National Heart, Lung, and Blood Institute (NHLBI)
Conditions
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Myeloid Leukemia (AML)Autoimmune LymphoproliferativeCommon Variable ImmunodeficiencyGATA2Graft-versus-host-diseaseHematologic Neoplasms
Phase 1
Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies
RecruitingNCT04959175
Start: 2021-09-23End: 2027-04-30Target: 320Updated: 2026-01-21
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
RecruitingNCT05436418
Start: 2022-11-18End: 2028-06-25Target: 260Updated: 2026-03-20
Phase 2
Matched Unrelated Donor Stem Cell Transplantation (MUD-SCT) After Dose-reduced Conditioning for Patients With Multiple Myeloma and Relapse After Autologous SCT
CompletedNCT00599495
Start: 2002-11-30End: 2009-12-31Updated: 2022-09-02
Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations
RecruitingNCT01861106
Start: 2013-07-24End: 2028-12-31Target: 144Updated: 2026-03-24
Allogeneic Hematopoietic Stem Cell Transplantation With Ixazomib for High Risk Multiple Myeloma (BMT CTN 1302)
CompletedNCT02440464
Start: 2015-08-31End: 2020-10-01Updated: 2023-01-04
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity
RecruitingNCT04339777
Start: 2020-09-22End: 2027-11-30Target: 66Updated: 2025-09-16
A Single-arm Trial of Prophylactic Tocilizumab for Acute GVHD Prevention After Haploidentical HSCT.
NCT04688021
Start: 2020-12-03End: 2024-12-31Target: 46Updated: 2023-02-21
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
RecruitingNCT05027945
Start: 2023-02-23End: 2026-07-01Target: 54Updated: 2026-04-02
Phase 3
Allogeneic HCT Using Nonmyeloablative Host Conditioning With TLI & ATG vs SOC in AML
TerminatedNCT00568633
Start: 2007-08-31End: 2015-12-31Updated: 2019-09-24
A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies
RecruitingNCT04547049
Start: 2020-09-01End: 2025-12-31Target: 176Updated: 2025-03-25
Unknown Phase
Treatment of Acute Lymphoblastic Leukemia HIGH RISK BCR / ABL NEGATIVE IN ADULTS
CompletedNCT01540812
Start: 2012-02-29End: 2019-12-01Updated: 2020-03-09
Risk Stratification-directed Therapy for AML With t(8;21) /AML1-ETO+
CompletedNCT02936089
Start: 2016-10-31End: 2022-12-31Updated: 2023-08-08
Treatment of Breakpoint Cluster Region-Abelson (BCR-ABL) Negative ALL in Adults
RecruitingNCT04179929
Start: 2019-11-25End: 2027-02-28Target: 300Updated: 2022-02-18
Alteration of Gut Microbiota Diversity after Allogeneic Hematopoietic Stem Cell Transplantation: A Pilot Study
Active, not recruitingTCTR20200629003
Start: 2020-07-01Target: 15Updated: 2026-03-30
ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL
Not yet recruitingNCT07454226
Start: 2026-03-01End: 2030-03-01Target: 30Updated: 2026-03-06