Alfacalcidol

DRUG18 trials

Sponsors

Calcilytix Therapeutics Inc., Chugai Pharmaceutical, Eisai Co., Ltd., Charite University, Berlin, Germany, Zealand University Hospital

Conditions

Accidental FallsAgedAlfacalcidol, Secondary Hyperparathyroidism, HemodialysisAsthmaAutosomal Dominant Hypocalcemia OR Primary Hypoparathyroidism Related to Other Cause But Complicated by Hypercalciuria Under TreatmentAutosomal Dominant Hypocalcemia Type 1 (ADH1)Cardiovascular DiseaseChronic Kidney Disease

Phase 2

Vitamin D and Cardiac Autonomic Tone in Hemodialysis

CompletedNCT01774812

University of CalgaryCardiovascular Disease, Sudden Cardiac Death

Start: 2013-01-31End: 2015-03-31Updated: 2016-08-31

Recombinant Human rhPTH(1-34) VS Association Alfacalcidol/Hydrochlorothiazide in Severe Primary Hypoparathyroidism

CompletedNCT02824718

Assistance Publique - Hôpitaux de ParisAutosomal Dominant Hypocalcemia OR Primary Hypoparathyroidism Related to Other Cause But Complicated by Hypercalciuria Under Treatment

Start: 2017-06-06End: 2020-05-28Updated: 2021-06-28

Phase 3

A New Active Vitamin D, ED-71 for Osteoporosis

CompletedNCT00144456

Chugai PharmaceuticalOsteoporosis

Start: 2004-09-30End: 2008-10-31Updated: 2013-08-09

Efficacy and Safety Study on Menatetrenone in the Treatment of Postmenopausal Osteoporosis Women

CompletedNCT00165698

Eisai Co., Ltd.Postmenopausal Osteoporosis

Start: 2005-05-31End: 2007-07-31Updated: 2014-07-22

The Effect of Alfacalcidol on Muscle Strength in Elderly Indonesian Women : A Randomized Controlled Trial

CompletedNCT02327091

Indonesia UniversityMuscle Weakness

Start: 2012-04-30End: 2012-12-31Updated: 2014-12-30

CALIBRATE: A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Encaleret Compared to Standard of Care in Participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1)

RecruitingCTIS2022-501398-38-00

Calcilytix Therapeutics Inc.Autosomal Dominant Hypocalcemia Type 1 (ADH1)

Start: 2023-09-02Target: 34Updated: 2026-01-16

Phase 4

Influence of Alfacalcidol on Falls in Osteopenic/Osteoporotic Postmenopausal Women (ALFA Study)

CompletedNCT00168909

Charite University, Berlin, GermanyFalls, Osteopenia, Osteoporosis, Postmenopausal

Start: 2003-06-30End: 2008-05-31Updated: 2008-05-09

Fall Prevention by Alfacalcidol and Training

WithdrawnNCT00483275

Ruhr University of BochumAccidental Falls, Aged, Chronic Renal Insufficiency

Start: 2007-06-30End: 2009-09-30Target: 484Updated: 2011-07-21

The Effect of Inactive and Active Vitamin D on Serum Sclerostin/dickkopf1 Levels

Seoul National University HospitalOsteoporosis

Start: 2013-01-31End: 2013-03-31Target: 88Updated: 2013-01-10

The Effect of Vitamin D Supplementation on the Pulmonary Functions of Adult Asthmatic Egyptian Patients

CompletedNCT02747381

Cairo UniversityAsthma

Start: 2014-08-31End: 2016-04-30Updated: 2016-04-21

Clinical Study of Treating Type 2 Diabetic Nephropathy With Alfacalcidol and Irbesartan

CompletedNCT03147677

The Third Xiangya Hospital of Central South UniversityType 2 Diabetic Nephropathy

Start: 2016-07-28End: 2018-12-30Updated: 2019-10-10

Active Vitamin D And Reduced Dose Prednisolone for Treatment in Minimal Change Nephropathy

CompletedNCT03210688

University of AarhusMinimal Change Disease, Nephrotic Syndrome

Start: 2018-05-01End: 2025-01-21Updated: 2025-01-24

Effect of Alfacalcidol to Respiratory Infection and Immune Response of Indonesian Elderly

Indonesia UniversityElderly Infection, Frail Elderly Syndrome

Start: 2017-01-10End: 2017-12-15Target: 110Updated: 2017-09-26

Effect of Alfacalcidol on Muscle Function in Osteoporosis Patients

Not yet recruitingNCT06272227

Yonsei UniversitySarcopenia

Start: 2024-02-13End: 2025-09-01Target: 340Updated: 2024-02-22

Unknown Phase

Treatment of Secondary Hyperparathyroidism in the Uremic Patient

TerminatedNCT00469599

Zealand University HospitalChronic Kidney Disease, Secondary Hyperparathyroidism, Vitamin D Deficiency

Start: 2007-07-31End: 2010-10-31Updated: 2011-04-04

Assessing the Effects of Alfacalcidol Intake on Expression of Involed Gene in Metabolism in Obese Subjects

Tehran University of Medical SciencesObesity

Start: 2012-01-31End: 2013-01-31Target: 94Updated: 2012-12-27

Eldecalcitol for GLucocorticoid Induced OsteopoRosIs Versus Alfacalcidol

e-GLORIA trial Protocol Review CommitteeOsteoporosis

Start: 2013-12-31Target: 400Updated: 2014-08-06

Effectiveness of Oral Alfacalcidol for Secondary Hyperparathyroidism in Chronic Hemodialysis Patients.

CompletedNCT02895061

Phramongkutklao College of Medicine and HospitalAlfacalcidol, Secondary Hyperparathyroidism, Hemodialysis

Start: 2015-01-31End: 2016-01-31Updated: 2017-05-31

Related Papers

A randomised controlled unblinded multicentre non-inferiority trial with activated vitamin D and prednisolone treatment in patients with minimal change nephropathy (ADAPTinMCN)

Trials2021-07-126 citations

Effect of alfacalcidol on the pulmonary function of adult asthmatic patients: A randomized trial.

2017-04-0113 citations

The VITAH Trial—Vitamin D Supplementation and Cardiac Autonomic Tone in Patients with End-Stage Kidney Disease on Hemodialysis: A Blinded, Randomized Controlled Trial

Nutrients2016-09-2813 citations

The influence of vitamin D analogs on calcification modulators, N-terminal pro-B-type natriuretic peptide and inflammatory markers in hemodialysis patients: a randomized crossover study

BMC Nephrology2014-08-1229 citations

The VITAH Trial Vitamin D supplementation and cardiac autonomic tone in hemodialysis: a blinded, randomized controlled trial

BMC Nephrology2014-08-0614 citations

Eldecalcitol normalizes bone turnover markers regardless of their pre-treatment levels.

2012-08-236 citations

A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures--a randomized, active comparator, double-blind study.

2011-07-19144 citations

Treatment of secondary hyperparathyroidism in haemodialysis patients: a randomised clinical trial comparing paricalcitol and alfacalcidol.

2009-09-2413 citations