AHB-137

DRUG11 trials

Sponsors

Ausperbio Therapeutics Inc., Ausper Biopharma Co., Ltd., AusperBio Therapeutics Inc., Grand Theravac Life Sciences (Hangzhou) Co., Ltd.

Conditions

Chronic Hepatitis BHepatitis B, Chronic

Phase 1

A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB)

Not yet recruitingNCT07876856

Ausper Biopharma Co., Ltd.Chronic Hepatitis B

Start: 2026-10-31End: 2029-06-20Target: 105Updated: 2026-10-19

A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB)

Not yet recruitingNCT07897448

Grand Theravac Life Sciences (Hangzhou) Co., Ltd.Chronic Hepatitis B

Start: 2026-10-31End: 2029-06-20Target: 105Updated: 2026-10-27

Phase 2

Study to Evaluate the Efficacy and Safety of AHB-137 in Treatment-naive Participants With Chronic Hepatitis B (CHB)

Active, not recruitingNCT06829329

Ausper Biopharma Co., Ltd.Chronic Hepatitis B

Start: 2024-12-13End: 2026-12-01Updated: 2026-07-29

A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

Active, not recruitingNCT06993480

Ausper Biopharma Co., Ltd.Chronic Hepatitis B

Start: 2025-07-15End: 2027-11-27Updated: 2026-08-10

A Multicenter Study of AHB-137 Injection Combined With Other Hepatitis B Drugs

RecruitingNCT07069569

Ausper Biopharma Co., Ltd.Chronic Hepatitis B

Start: 2025-06-08End: 2028-01-15Target: 200Updated: 2026-07-29

A Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

RecruitingNCT07137910

Ausper Biopharma Co., Ltd.Chronic Hepatitis B

Start: 2025-09-04End: 2027-06-01Target: 200Updated: 2026-08-05

Phase 2 Study of AHB-137 in HBeAg Negative Chronic Hepatitis B (CHB) Participants in Asia Pacific Region

RecruitingNCT07370207

AusperBio Therapeutics Inc.Hepatitis B, Chronic

Start: 2026-03-06End: 2028-12-31Target: 84Updated: 2026-10-13

A Study to Evaluate AHB-137 Injection in Treatment-naïve Participants With Chronic Hepatitis B

RecruitingNCT07635186

Ausper Biopharma Co., Ltd.Chronic Hepatitis B

Start: 2026-06-05End: 2028-06-20Target: 320Updated: 2026-07-29

Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions

RecruitingNCT07654283

AusperBio Therapeutics Inc.Hepatitis B, Chronic

Start: 2026-09-01End: 2028-07-26Target: 70Updated: 2026-10-29

Aspire-202: A Phase 2 Multi-center, Randomized, Open-label Study to Assess the Efficacy and Safety of AHB-137 in Nucleos(t)ide Analogue-treated Participants with Chronic Hepatitis B in the North America and Europe Regions

Not yet recruitingCTIS2025-524159-30-00

Ausperbio Therapeutics Inc.Chronic Hepatitis B

Target: 22Updated: 2026-10-23

Phase 3

Study of AHB-137 in Participants With Chronic Hepatitis B (CHB) Treated With Nucleos(t)Ide Analogues (NAs)(AUSHINE)

Active, not recruitingNCT07246889

Ausper Biopharma Co., Ltd.Chronic Hepatitis B

Start: 2025-08-12End: 2027-10-31Updated: 2026-05-04