Adult stem cells

BIOLOGICAL4 trials

Sponsors

Murphy, Michael P., MD, The University of Texas Health Science Center, Houston

Conditions

AnginaChronic Ischemic Heart DiseaseIschemic CardiomyopathyLeft Ventricular DysfunctionPeripheral Vascular Diseases

Phase 1

Safety Study of Using Stem Cells to Stimulate Development of New Blood Vessels in Peripheral Vascular Disease

Murphy, Michael P., MDPeripheral Vascular Diseases

Start: 2004-12-31End: 2007-12-31Target: 20Updated: 2005-06-24

Phase 2

Use of Adult Autologous Stem Cells in Treating People Who Have Had a Heart Attack (The TIME Study)

CompletedNCT00684021

The University of Texas Health Science Center, HoustonLeft Ventricular Dysfunction

Start: 2008-07-31End: 2012-11-30Updated: 2015-06-30

Use of Adult Autologous Stem Cells in Treating People 2 to 3 Weeks After Having a Heart Attack (The Late TIME Study)

CompletedNCT00684060

The University of Texas Health Science Center, HoustonLeft Ventricular Dysfunction

Start: 2008-07-31End: 2012-02-29Updated: 2015-07-10

Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study)

CompletedNCT00824005

The University of Texas Health Science Center, HoustonAngina, Chronic Ischemic Heart Disease, Ischemic Cardiomyopathy +1

Start: 2009-03-31End: 2012-05-31Updated: 2015-07-01

Related Papers

TIME Trial: Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function

Circulation Research2017-12-0561 citations

Peripheral Blood Cytokine Levels After Acute Myocardial Infarction

Circulation Research2017-05-1140 citations

Abstract 12445: A Detailed Analysis of Peripheral Blood Cytokines 2-3 weeks After Acute Myocardial Infarction: IL-6-Related Impairment of Bone Marrow Function

Circulation2015-11-10

Bone Marrow Characteristics Associated With Changes in Infarct Size After STEMI

Circulation Research2014-11-1959 citations

Detailed Analysis of Bone Marrow From Patients With Ischemic Heart Disease and Left Ventricular Dysfunction

Circulation Research2014-08-1966 citations

Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial.

2012-12-01278 citations

Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial.

2012-03-24314 citations

Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial.

2011-11-14287 citations