Adalimumab Placebo
Sponsors
Abbvie Deutschland GmbH & Co. KG, AbbVie (prior sponsor, Abbott), National Institute of Allergy and Infectious Diseases (NIAID), CSL Behring, Eli Lilly and Company
Conditions
Autoimmune DiseasesColitis, UlcerativeDiabetes MellitusDiabetes Mellitus, Type 1Early Rheumatoid ArthritisHypoglycemiaRheumatoid ArthritisUlcerative Colitis
Phase 1
Phase 2
Phase 3
Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis
CompletedNCT00195663
Start: 2000-12-31End: 2012-04-30Updated: 2013-07-12
A Study in Moderate to Severe Rheumatoid Arthritis
CompletedNCT01710358
Start: 2012-10-31End: 2015-09-30Updated: 2019-09-18
A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors
CompletedNCT02163759
Start: 2014-11-04End: 2020-03-19Updated: 2021-07-23
A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors
CompletedNCT02171429
Start: 2014-11-14End: 2020-05-25Updated: 2021-07-23
An Efficacy and Safety Study of Vedolizumab Intravenous (IV) Compared to Adalimumab Subcutaneous (SC) in Participants With Ulcerative Colitis
CompletedNCT02497469
Start: 2015-06-29End: 2019-01-18Updated: 2020-01-28
A Phase 3b/4 Randomized, Double-Blind, Double-Dummy, Active-Comparator Controlled Study, Comparing the Efficacy and Safety of Upadacitinib Versus Adalimumab in Subjects with Moderate to Severe Rheumatoid Arthritis on a stable background of MTX and who had an Inadequate Response or Intolerance to a Single TNF Inhibitor (SELECT- SWITCH)
Active, not recruitingCTIS2022-502578-18-00
Start: 2023-11-07Target: 165Updated: 2025-09-16
Phase 4
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