Aceclidine+Brimonidine combination ophthalmic solution

DRUG6 trials

Sponsors

LENZ Therapeutics, Inc, Corxel Pharmaceuticals

Conditions

Eye DiseasesMiosisNear VisionPresbyopiaRefractive ErrorRefractive Errors

Phase 2

Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia

CompletedNCT05294328

LENZ Therapeutics, IncEye Diseases, Presbyopia, Refractive Errors

Start: 2022-05-05End: 2022-09-10Updated: 2024-09-05

Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia

CompletedNCT05431543

LENZ Therapeutics, IncEye Diseases, Presbyopia, Refractive Errors

Start: 2022-08-06End: 2022-12-14Updated: 2024-09-05

Phase 3

Phase 3 Evaluation of the Safety and Efficacy of LNZ100 & LNZ101 for the Treatment of Presbyopia

CompletedNCT05656027

LENZ Therapeutics, IncEye Diseases, Near Vision, Presbyopia +1

Start: 2022-12-19End: 2024-01-25Updated: 2026-02-25

Phase 3 Efficacy Study of LNZ100 & LNZ101 for the Treatment of Presbyopia

CompletedNCT05728944

LENZ Therapeutics, IncEye Diseases, Near Vision, Presbyopia +1

Start: 2023-03-06End: 2024-01-24Updated: 2026-02-25

Phase 3 Safety Study for the Treatment of Presbyopia Subjects

CompletedNCT05753189

LENZ Therapeutics, IncEye Diseases, Miosis, Near Vision +1

Start: 2023-02-21End: 2024-02-09Updated: 2024-12-18

Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia

CompletedNCT06045299

Corxel PharmaceuticalsEye Diseases, Miosis, Near Vision +1

Start: 2023-09-27End: 2025-01-27Updated: 2025-03-03