5% dextrose in water

DRUG7 trials

Sponsors

Tranzyme, Inc., John A. Schirger, Mast Therapeutics, Inc.

Conditions

Chronic Heart FailureDiabetes MellitusGastrointestinal DysmotilityGastroparesisHeart FailurePostoperative IleusRenal Insufficiency

Phase 1

Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Diabetic Gastroparesis

CompletedNCT00639808

Tranzyme, Inc.Diabetes Mellitus, Gastroparesis

Start: 2006-08-31End: 2008-03-31Updated: 2008-03-20

Effects of Chimeric Natriuretic Peptide Versus Placebo in Stable Heart Failure and Moderate Renal Dysfunction

WithdrawnNCT01407900

John A. SchirgerHeart Failure, Renal Insufficiency

Start: 2014-01-31End: 2014-02-28Updated: 2014-06-17

Phase 2

Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Severe Diabetic Gastroparesis

CompletedNCT00612014

Tranzyme, Inc.Diabetes Mellitus, Gastroparesis

Start: 2007-10-31End: 2009-03-31Updated: 2012-12-07

Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery

CompletedNCT00617552

Tranzyme, Inc.Postoperative Ileus

Start: 2007-07-31End: 2008-08-31Updated: 2012-12-07

Evaluation of Vepoloxamer in Chronic Heart Failure

TerminatedNCT02596477

Mast Therapeutics, Inc.Chronic Heart Failure

Start: 2015-10-31Updated: 2016-10-28

Phase 3

Ulimorelin Study of Efficacy and Safety (ULISES 007)

CompletedNCT01285570

Tranzyme, Inc.Gastrointestinal Dysmotility

Start: 2011-01-31End: 2012-01-31Updated: 2012-07-26

Ulimorelin Study of Efficacy and Safety (ULISES 008)

CompletedNCT01296620

Tranzyme, Inc.Gastrointestinal Dysmotility

Start: 2011-02-28End: 2012-03-31Updated: 2012-07-26

Related Papers

Safety and efficacy of ulimorelin administered postoperatively to accelerate recovery of gastrointestinal motility following partial bowel resection: results of two randomized, placebo-controlled phase 3 trials.

2013-07-0137 citations