3% hypertonic saline

DRUG10 trials

Conditions

Acute BronchiolitisAcute Liver FailureBRONCHIOLITISBrain ConcussionBronchiolitisCorneal EdemaFluid ResuscitationHyponatremia Symptomatic

Phase 1

Effect of Fluid Resuscitation on Lactate in Traumatic Injury Patients

Not yet recruitingNCT06370975

Assiut UniversityFluid Resuscitation

Start: 2024-08-01End: 2025-09-30Target: 150Updated: 2024-04-17

Phase 3

The SABRE Trial of Hypertonic Saline in Acute Bronchiolitis

CompletedNCT01469845

Sheffield Children's NHS Foundation TrustAcute Bronchiolitis

Start: 2011-10-31End: 2014-01-31Updated: 2015-03-25

Phase 4

Efficacy and Safety of Rapid Intermittent Compared With Slow Continuous Correction in Severe Hyponatremia Patients

CompletedNCT02887469

Seoul National University HospitalHyponatremia Symptomatic

Start: 2016-08-31End: 2019-09-30Updated: 2020-04-09

Unknown Phase

Use of Salt-Water Solution to Improve Symptoms in Concussion

CompletedNCT00142090

Rady Children's Hospital, San DiegoBrain Concussion, Post-Concussion Symptoms

Start: 2004-11-30End: 2007-07-31Updated: 2009-02-03

Nebulized Hypertonic Saline Treatment in Hospitalized Children With Moderate to Severe Viral Bronchiolitis

CompletedNCT01120496

Chongqing Medical UniversityBronchiolitis

Start: 2008-11-30End: 2009-11-30Updated: 2010-05-11

Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis

CompletedNCT02029040

University of Texas Southwestern Medical CenterAcute Bronchiolitis

Start: 2013-12-31End: 2014-12-31Updated: 2019-01-25

Role of Hypertonic Saline Versus Mannitol in the Management of Raised Intracranial Pressure in Patients With ALF

CompletedNCT02460510

Institute of Liver and Biliary Sciences, IndiaAcute Liver Failure

Start: 2014-06-30End: 2015-11-30Updated: 2016-02-17

Phase I Assessment of Hypertonic Saline in Moderate to Severe Asthmatics

CompletedNCT03556683

University of North Carolina, Chapel HillModerate to Severe Asthma

Start: 2018-10-01End: 2024-06-06Updated: 2025-08-05

Comparison of 3% Hypertonic Saline and Salbutamol in Children With Bronchiolitis

Not yet recruitingNCT06665711

University of Health Sciences LahoreBRONCHIOLITIS

Start: 2024-12-03End: 2025-03-10Target: 100Updated: 2024-10-30

Comparison of 5% Hypertonic Saline Versus 3% Hypertonic Saline in Resolution of Post-operative Corneal Edema.

CompletedNCT07605273

Muhammad Aamir LatifCorneal Edema

Start: 2025-06-01End: 2025-12-31Updated: 2026-05-22

Related Papers

Risk of Overcorrection in Rapid Intermittent Bolus vs Slow Continuous Infusion Therapies of Hypertonic Saline for Patients With Symptomatic Hyponatremia

JAMA Internal Medicine2020-10-26103 citations

Efficacy and safety of rapid intermittent correction compared with slow continuous correction with hypertonic saline in patients with moderately severe or severe symptomatic hyponatremia: study protocol for a randomized controlled trial (SALSA trial).

2017-03-2910 citations

Saline in acute bronchiolitis RCT and economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review.

2015-08-0111 citations

SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis

Thorax2014-11-11111 citations