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18F-fluoromisonidazole

OTHER10 trials

Sponsors

Okayama university, M.D. Anderson Cancer Center, National Cancer Institute (NCI), University College London (UCL) Cancer Institute, Stanford University

Conditions

Adult Liver CarcinomaAdvanced Malignant Solid NeoplasmBCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaBCLC Stage a Hepatocellular CarcinomaBrain MetastasesBreast CancerCervical Adenocarcinoma

Early Phase 1

BOLD MRI and FMISO PET for the Assessment of Hypoxic Tumor Microenvironment in Patients with Oligometastatic Liver Cancer Undergoing Yttirum-90 Selective Internal Radiation Therapy
CompletedNCT05250895
Emory UniversityBCLC Stage a Hepatocellular Carcinoma, BCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma +1
Start: 2022-04-28End: 2025-02-26Updated: 2025-03-13
Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy
RecruitingNCT05996432
Vanderbilt-Ingram Cancer CenterBrain Metastases, Head and Neck Squamous Cell Carcinoma
Start: 2023-05-17End: 2029-05-31Target: 48Updated: 2024-09-23

Phase 2

FDG and FMISO PET Hypoxia Evaluation in Cervical Cancer
CompletedNCT00559377
National Cancer Institute (NCI)Cervical Adenocarcinoma, Cervical Squamous Cell Carcinoma, Stage IB Cervical Cancer +5
Start: 2007-11-30End: 2014-05-31Updated: 2016-12-30
18F-Fluoromisonidazole and Fludeoxyglucose F 18 PET/CT Patients With Soft Tissue Sarcoma
TerminatedNCT01169350
National Cancer Institute (NCI)Recurrent Adult Soft Tissue Sarcoma, Stage I Adult Soft Tissue Sarcoma, Stage II Adult Soft Tissue Sarcoma +2
Start: 2010-02-28End: 2013-08-31Updated: 2017-11-17
Study of Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy in Patients With Stage III Non-small Cell Lung Cancer
NCT01507428
National Cancer Institute (NCI)Stage IIIA Lung Non-Small Cell Cancer AJCC v7, Stage IIIB Lung Non-Small Cell Cancer AJCC v7, Stage III Lung Non-Small Cell Cancer AJCC v7
Start: 2012-02-22End: 2021-08-01Updated: 2021-04-29
A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors
Active, not recruitingNCT02498613
National Cancer Institute (NCI)Advanced Malignant Solid Neoplasm, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Lung Small Cell Carcinoma +23
Start: 2016-08-31End: 2026-04-10Updated: 2025-09-25
[18F]FMISO PET/CT After Transcatheter Arterial Embolization in Imaging Tumors in Patients With Liver Cancer
CompletedNCT02695628
Stanford UniversityAdult Liver Carcinoma, Liver Cirrhosis
Start: 2016-09-13End: 2018-10-31Updated: 2024-01-31

Unknown Phase

Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole
WithdrawnNCT00038038
M.D. Anderson Cancer CenterHead and Neck Neoplasms, Metastases, Neoplasm, Squamous Cell Carcinoma
Start: 1994-01-31End: 2003-06-30Updated: 2012-08-01
Positron Emission Tomography/Computed Tomography Scanning Before Surgery in Patients With Non-Small Cell Lung Cancer, Colorectal Cancer, Breast Cancer, Esophageal Cancer, or Head and Neck Cancer
NCT01254591
University College London (UCL) Cancer InstituteBreast Cancer, Colorectal Cancer, Esophageal Cancer +2
Start: 2006-11-30Target: 500Updated: 2013-08-26
Hypoxia imaging in the brain and spinal cord of ALS
Active, not recruitingJPRN-UMIN000026862
Okayama universityneurological diseases
Start: 2017-05-01Target: 15Updated: 2025-07-18

Related Papers

Primary Results of NRG-RTOG1106/ECOG-ACRIN 6697: A Randomized Phase II Trial of Individualized Adaptive (chemo)Radiotherapy Using Midtreatment <sup>18</sup> F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Stage III Non–Small Cell Lung Cancer
Journal of Clinical Oncology2024-10-0429 citations
Limitations of Fluorine 18 Fluoromisonidazole in Assessing Treatment-induced Tissue Hypoxia after Transcatheter Arterial Embolization of Hepatocellular Carcinoma: A Prospective Pilot Study
Radiology Imaging Cancer2022-04-296 citations
NRG-RTOG 1106/ACRIN 6697: A phase IIR trial of standard versus adaptive (mid-treatment PET-based) chemoradiotherapy for stage III NSCLC—Results and comparison to NRG-RTOG 0617 (non-personalized RT dose escalation).
Journal of Clinical Oncology2021-05-2031 citations
Analysis of homologous recombination DNA repair gene mutation status in patients with metastatic small cell lung cancer treated with cediranib and olaparib on NCI 9881 study.
Journal of Clinical Oncology2021-05-20
Preliminary efficacy data of platinum-pretreated small cell lung cancer (SCLC) cohort of NCI 9881 study: A phase II study of cediranib in combination with olaparib in advanced solid tumors.
Journal of Clinical Oncology2020-05-2010 citations
Preliminary efficacy data of triple-negative breast cancer cohort of NCI 9881 study: A phase II study of cediranib in combination with olaparib in advanced solid tumors.
Journal of Clinical Oncology2020-05-207 citations
Delineation of lung cancer with FDG PET/CT during radiation therapy.
2018-11-1216 citations
FDG and FMISO PET-guided dose escalation with intensity-modulated radiotherapy in lung cancer.
2018-10-2332 citations
Abstract IA16: Midtreatment metabolic imaging as a biomarker of treatment response
Clinical Cancer Research2017-11-30