18F-DOPA

DRUG8 trials

Sponsors

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Children's Hospital of Philadelphia, Institut Claudius Regaud, University of Alberta

Conditions

ACTHAutonomic FailureBeckwith-Wiedemann SyndromeBrain GliomaBrain TumorCongenital HyperinsulinismCongenital Hyperinsulinism (CHI)Cushing Syndrome

Phase 2

Studies of Elevated Parathyroid Activity

CompletedNCT00001277

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Hypercalcemia, Hyperparathyroidism, MEN1 +2

Start: 1993-12-15End: 2020-12-23Updated: 2022-06-07

New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome

CompletedNCT00001849

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Cushing Syndrome, Endocrine Disease

Start: 1999-05-20End: 2019-04-26Updated: 2021-04-14

Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Ectopic Cushing Syndrome

RecruitingNCT02019706

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)ACTH, Cushing's Syndrome

Start: 2014-02-12End: 2030-12-31Target: 80Updated: 2026-04-02

Phase 3

18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety

CompletedNCT03042416

University of AlbertaBrain Glioma, Congenital Hyperinsulinism, Neuroblastoma +2

Start: 2017-06-29End: 2021-06-02Updated: 2022-01-10

18F-DOPA II - PET Imaging Optimization

RecruitingNCT04706910

University of AlbertaBrain Tumor, Congenital Hyperinsulinism, Lewy Body Disease +3

Start: 2021-01-20End: 2027-12-01Target: 800Updated: 2026-02-09

Unknown Phase

18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia

Children's Hospital of PhiladelphiaBeckwith-Wiedemann Syndrome, Congenital Hyperinsulinism (CHI), Insulinoma

Updated: 2025-04-02

Prospective Study Evaluating the Medullary Thyroid Cancer Management's Care Using PET F-DOPA in Patients With a High Level of Postoperative Residual Thyrocalcitonin

CompletedNCT02856347

Institut Claudius RegaudMedullary Thyroid Cancer

Start: 2017-03-22End: 2020-12-20Updated: 2025-11-18

Clinical Laboratory Evaluation of Chronic Autonomic Failure

Active, not recruitingNCT03648905

National Institute of Neurological Disorders and Stroke (NINDS)Autonomic Failure, Multiple System Atrophy, Parkinson's Disease

Start: 2018-09-06End: 2029-12-31Updated: 2026-04-01