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Most of the Acute Stress Reduction from Guided Slow Breathing Occurs Within the First 2.5 Minutes: A Single-Arm Pilot Study in Medical Students

Most of the Acute Stress Reduction from Guided Slow Breathing Occurs Within the First 2.5 Minutes: A Single-Arm Pilot Study in Medical Students

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260731006
Enrollment
30
Registered
2026-07-31
Start date
2025-09-17
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Academic Stress Academic stress Medical students Slow breathing Vagus nerve stimulation Heart rate variability Biofeedback

Interventions

A single 10-minute session of visually guided slow breathing was delivered using a pre-recorded video presented on an iPad. The video used animated water-droplet cues to pace respiration at approximat
Experimental Behavioral
Visual-guided slow breathing at 6 breaths per minute

Sponsors

Faculty of Medicine, Chiang Mai University
Lead Sponsor
Chiang Mai University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Medical student at Chiang Mai University Smartwatch derived stress score 80 or more measured by Garmin Venu 3 Self reported stress rating 80 or more on a numerical rating scale of 0 to 100 Ability to provide electronic informed consent

Exclusion criteria

Exclusion criteria: Inability to provide informed consent Pre-existing neurological conditions including epilepsy, seizures, or other neurological disorders Severe cardiovascular conditions such as arrhythmia, heart disease, or hypertension Current or recent use of medications affecting heart rate or stress response such as beta blockers or antidepressants Panic disorder or frequent uncontrolled panic attacks Moderate to severe chronic obstructive pulmonary disease Uncontrolled asthma, frequent exacerbations, or requirement for high dose corticosteroid treatment History of recurrent hyperventilation syndrome

Design outcomes

Primary

MeasureTime frame
Smartwatch-derived stress score Baseline (0 min) and at 2.5, 5, 7.5 and 10 minutes during the session Garmin Venu 3 stress score ,Self-reported stress score Immediately before and immediately after the 10-minute session Self-reported numerical rating scale

Secondary

MeasureTime frame
Heart rate Baseline (0 min) and end of session (10 min) Garmin Venu 3, beats per minute,Depressive symptoms Baseline only (for subgroup analysis) Patient Health Questionnaire-9 (PHQ-9),Anxiety symptoms Baseline only (for subgroup analysis) Generalized Anxiety Disorder-7 (GAD-7),Acceptability and tolerability Immediately after the intervention Open-ended qualitative questions on perceived effects, side effects, and willingness to repeat the practice

Countries

Thailand

Contacts

Public Contactbenchalak maneeton

Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

narong.m@cmu.ac.th053935422

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026