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Comparison of Hct level in near term and term Infants: intact umbilical cord milking versus cut umbilical cord milking versus delayed cord clamping

Comparison of Hct level in near term and term Infants: intact umbilical cord milking versus cut umbilical cord milking versus delayed cord clamping

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260720002
Enrollment
254
Registered
2026-07-20
Start date
2026-08-24
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Near term and term Infants at GA 35 - 40+6 weeks undergoing different umbilical cord management at birth. Intact Umbilical Cord Milking (I-UCM), Cut Umbilical Cord Milking (C-UCM), Delayed Cord Clamping (DCC), Hematocrit, Hyperbilirubinemia, Neonatal hypothermia, Neonatal polycythemia

Interventions

Intact umbilical cord milking (I-UCM) refers to milking the umbilical cord while it remains intact and connected between the placenta and the newborn. Approximately 25 cm. of the umbilical cord will b
s umbilical stump.,Cut umbilical cord milking (C-UCM) refers to milking the umbilical cord after it has been cut from the placenta. Immediately after birth, the umbilical cord will be clamped and cut
s umbilicus. The isolated cord segment will then be milked toward the infant. After cord milking is completed, the cord will be clamped and cut again, leaving a stump approximately 2-3 cm. from the in
s umbilicus.,Delayed cord clamping (DCC) refers to delaying clamping of the umbilical cord for at least 30 seconds after birth before clamping and cutting the cord, leaving a cord stump approximately
s umbilicus.
Intact umbilical cord milking (I-UCM),Cut umbilical cord milking (C-UCM),Delayed cord clamping (DCC)

Sponsors

Bhumibol Adulyadej Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Pregnant women who provide written informed consent. 2. Singleton pregnancy.

Exclusion criteria

Exclusion criteria: 1. Pregnant women aged < 18 years 2. Umbilical cord length <25 cm or abnormal umbilical cord anatomy 3. Newborns requiring immediate neonatal resuscitation or respiratory support according to the 2025 American Heart Association and American Academy of Pediatrics Neonatal Resuscitation Guidelines. 4. Major congenital anomalies or prenatally diagnosed fetal structural abnormalities. 5. Obstetric emergencies requiring immediate delivery, including umbilical cord prolapse, placental abruption, placenta previa, preeclampsia, uterine rupture, severe maternal hemorrhage, or maternal shock. 6. Maternal infection with human immunodeficiency virus (HIV), syphilis, or hepatitis B virus (HBV). 7. Maternal Rh-negative blood type.

Design outcomes

Primary

MeasureTime frame
Neonatal hematocrit Within 48 hours after birth Venous hematocrit (%) measured from peripheral venous blood using an automated hematology analyzer.

Secondary

MeasureTime frame
Neonatal microbilirubin level Within 48 hours after birth Total serum bilirubin (mg/dL) measured by standard laboratory methods.,NICU admission During birth hospitalization Admission to the neonatal intensive care unit (Yes/No) obtained from medical records.,Neonatal complications During birth hospitalization Presence of neonatal complications such as respiratory distress, polycythemia, hypoglycemia, or jaundice requiring treatment, assessed from medical records.,Apgar score 1 minute and 5 minutes after birth Apgar score assessed at 1 and 5 minutes after birth.,Maternal blood loss Immediately after delivery Estimated blood loss (mL) recorded at delivery.

Countries

Thailand

Contacts

Public ContactKullaya Suwantaweesuk

Bhumibol Adulyadej hospital

kullaya.med@gmail.com025347000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026