Effect of popliteal plexus block on opioid consumption following arthroscopic anterior cruciate ligament reconstruction: a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260718008

Enrollment

Registered

2026-07-18

Start date

2026-07-20

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain following arthroscopic anterior cruciate ligament reconstruction Anterior Cruciate Ligament Reconstruction Postoperative pain Popliteal plexus block Peripheral nerve block

Interventions

Participants will receive an ultrasound-guided femoral triangle block (FTB) with 20 mL of 0.25% bupivacaine and a popliteal plexus block (PPB) with 10 mL of 0.25% bupivacaine before induction of gener

Experimental Procedure/Surgery,Sham Comparator Procedure/Surgery

Femoral Triangle Block plus Popliteal Plexus Block,Femoral Triangle Block plus Sham Popliteal Plexus Block

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) I-III classification 2. Undergoing unilateral arthroscopic ACLR 3. Weight >= 40 kg

Exclusion criteria

Exclusion criteria: 1. Patients refuse to participate in study 2. BMI >= 35 kg/m2 3. Revision knee surgery 4. Allergy to study medications: Bupivacaine, Morphine, Paracetamol, Parecoxib, Naproxen 5. Chronic opioid use 6. Neuromuscular deficiency 7. Contraindications to peripheral nerve block: coagulopathy INR > 3, skin infection at procedure site 8. Serious medical conditions: severe renal impairment (CrCl < 30), severe hepatic impairment, severe cerebro-cardiovascular disease (Congestive heart failure NYHAII-IV, post CABG, established ischemic heart disease) or peripheral artery disease 9. Asthma, urticaria or allergic-type reaction after taking aspirin, NSAIDs or COX-2 10. Diabetes mellitus 11. Pregnancy

Design outcomes

Primary

Measure	Time frame
Postoperative opioid consumption first 24 postoperative hours Total opioid consumption via patient-controlled analgesia (PCA)	—

Secondary

Measure	Time frame
Pain intensity at rest and during movement 0, 4, 8, 12, and 24 hours postoperatively Numerical rating scale 0-10,Ankle range of motion (plantar flexion and dorsiflexion) Preoperative, 4 hours and 24 hours postoperatively measured using a goniometer in degree,Motor power (plantar flexion and dorsiflexion) Preoperative, 4 hours and 24 hours postoperatively grading on a 3 - point scale (0 normal, 1 weak, 2 absent),Sensory function was tested by pinprick in the tibial nerve and common peroneal nerve territories 4 hours and 24 hours postoperatively grading on 3 - point scale (0 normal, 1 decreased, 2 absent)	—

Measure

Time frame

Pain intensity at rest and during movement 0, 4, 8, 12, and 24 hours postoperatively Numerical rating scale 0-10,Ankle range of motion (plantar flexion and dorsiflexion) Preoperative, 4 hours and 24 hours postoperatively measured using a goniometer in degree,Motor power (plantar flexion and dorsiflexion) Preoperative, 4 hours and 24 hours postoperatively grading on a 3 - point scale (0 normal, 1 weak, 2 absent),Sensory function was tested by pinprick in the tibial nerve and common peroneal nerve territories 4 hours and 24 hours postoperatively grading on 3 - point scale (0 normal, 1 decreased, 2 absent)

—

Countries

Thailand

Contacts

Public ContactKaruna Sutthibenjakul

Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University

aptx_conan@hotmail.com0744516512

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026