Knee Osteoarthritis Knee osteoarthritis Osteoarthritis Cabbage serum Herbal therapy Pain relief Functional outcomes Oxford Knee Score Numeric Rating Scale
Conditions
Interventions
Topical application of cabbage-derived serum once daily for 12 weeks, in addition to standard care (physiotherapy and oral analgesics).,Standard care for all participants includes physiotherapy and or
Experimental Drug,Placebo Comparator Other
Cabbage serum,Placebo serum
Sponsors
Princess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Aged 50 years or older; male or female. 2. Early to moderate knee osteoarthritis, defined by clinical symptoms of knee pain and stiffness consistent with osteoarthritis, and radiographic Kellgren-Lawrence grade 2 or 3 in the target knee within the past 12 months. 3. Underwent bone mineral density (BMD) assessment via DXA scan. 4. Underwent X-rays of both hips.
Exclusion criteria
Exclusion criteria: 1. History of hip fractures or cracks on both sides. 2. Presence of conditions affecting the femur, such as metabolic bone disease, bone tumors, or bone deformity. 3. Physical condition unsuitable for undergoing X-rays and bone density testing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain severity Baseline and 12 weeks post-intervention Numeric Rating Scale (NRS 0-10) | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee function Baseline and 12 weeks Oxford Knee Score (OKS 0-48),Favorable clinical response rate 12 weeks Proportion achieving 3-point OKS improvement,Adverse events 12 weeks Clinical assessment and documentation,Patient satisfaction 12 weeks Satisfaction questionnaire | — |
Countries
Thailand
Contacts
Public ContactThanapon Chobpenthai
Princess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy
Outcome results
None listed