Longitudinal Trajectory of Gut Microbiome Diversity and Composition in Preterm Infants During NICU Hospitalization in Thailand

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20260713002

Enrollment

106

Registered

2026-07-13

Start date

2026-07-08

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm infant born less than or equal to 33 weeks. Preterm, Gut Microbiome Diversity, Vaginal delivery, Cesarean section, Route of delivery

Interventions

Infants delivered via Vaginal delivery,Infants delivered via Cesarean section.

Other,Other

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Preterm infant born less than or equal to 33 weeks at Siriraj hospital, Thailand 2. Parental consent obtained

Exclusion criteria

Exclusion criteria: 1. Congenital gastrointestinal tract anomalies. 2. Major congenital anomalies or chromosomal abnormalities. 3. Critical congenital heart defects, except patent ductus arteriosus and atrial septal defect. 4. Mothers receiving immunosuppressive therapy, or those with severe immune system disorders or infectious diseases. 5. Infants born to mothers aged less than 18 years of age

Design outcomes

Primary

Measure	Time frame
Bifidobacterium abundance Complete collection of stool samples Short read DNA	—

Secondary

Measure	Time frame
Probiotic use Before hospital discharge Medical record,diversity each time point Short read DNA	—

Countries

Thailand

Contacts

Public ContactPunnanee Wutthigate

Faculty of Medicine Siriraj Hospital, Mahidol University

punnanee.wut@mahidol.ac.th024195713

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026