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Effect of intraoperative triamcinolone injection at wound edges on thyroidectomy scar outcomes: a randomized, assessor-blinded controlled trial

Effect of intraoperative triamcinolone injection at wound edges on thyroidectomy scar outcomes: a randomized, assessor-blinded controlled trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260711017
Enrollment
72
Registered
2026-07-11
Start date
2026-07-06
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adults aged 18-75 years who undergo open thyroid lobectomy or total thyroidectomy through a conventional transverse Kocher incision Thyroidectomy Triamcinolone Acetonide Scar Hypertrophic scar Keloid

Interventions

triamcinolone acetonide intradermal injection,no intervention
Experimental Drug,No Intervention No treatment
Triamcinolone acetonide group,Control group

Sponsors

Mahidol university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: -Plan for open thyroidectomy (lobectomy/total) with Kocher incision -Able to come for follow up up to 6 months

Exclusion criteria

Exclusion criteria: -History of keloid/hypertrophic scar at any part of the body -Undergone open thyroidectomy (lobectomy/total) with Lateral neck incision -History of neck surgery or have scar across the neck area -Underlying diseases that interfere with healing process eg. uncontrolled diabetes mellitus, immunocompromised host, autoimmune disease -History of allergy to triamcinolone acetonide -Preoperatively or Intraoperatively have contaminated wound or active infection at neck area -Unable to follow up up to 6 months

Design outcomes

Primary

MeasureTime frame
Patient's scar satisfication 6 months after operation Patient Scar Assessment Scale component of the Patient and Observer Scar Assessment Scale

Secondary

MeasureTime frame
Patient's scar satisfication 3 months after operation Patient Scar Assessment Scale component of the Patient and Observer Scar Assessment Scale,Assessor evaluation of patient's scar 3,6 months after operation Patient Scar Assessment Scale component of the Patient and Observer Scar Assessment Scale,Assessor evaluation of patient's scar 3,6 months Scar width will be measured in millimeters

Countries

Thailand

Contacts

Public ContactRawisara Sritrakool

Department of Otolaryngology

rawisara.sri@mahidol.ac.th022011515

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026