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Evaluating the Necessity of Preoperative Intravenous Fluid for Preventing Hypotension in Elective Colonoscopy: A Randomized Controlled Trial

Evaluating the Necessity of Preoperative Intravenous Fluid for Preventing Hypotension in Elective Colonoscopy: A Randomized Controlled Trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260711005
Enrollment
500
Registered
2026-07-11
Start date
2026-06-28
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective Colonoscopy Colonoscope, Intravenous fluid

Interventions

Group Non-Intravenous Fluid (Intervention Group, n 250) Patients will not receive pre-procedural IV fluid infusion. IV fluid will only be used to flush the line following sedation administration,Group
No Intervention No treatment,Placebo Comparator Drug
Non-IV fluid,IV fluid

Sponsors

Department of Anesthesiology Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective colonoscopy 2. Aged between 18 and 80 years 3. ASA Physical Status 1 or 2

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Contraindications to fluid administration 3. Signs of severe dehydration or hypotension before procedure evaluation 4. History of allergy to propofol or fentanyl 5. BMI less than 20 kg per meter squares or more than 30 kg per meter squares 6. Diagnosed with obstructive sleep apnea 7. Chronic alcohol consumption, benzodiazepine use, or opioid use 8. Oral intake of food or water within 2 hours before the procedure 9. Hypertensive patients who missed their regular antihypertensive medication

Design outcomes

Primary

MeasureTime frame
Incidecne of hypotension Intraoperation Percentage

Secondary

MeasureTime frame
Volume of IV fluid for resuscitation Intraoperation mL,Dose vasopressor Intraoperation mg,Dose of propofol Intraoperation mg,Dose of fentanyl Intraoperation mcg,Procedure duration Intraoperation minutes,Recovery time in PACU Postoperation minutes,Patient satisfactory Postoperation VAS ,Endoscopist satisfactory Postoperation VAS

Countries

Thailand

Contacts

Public ContactNatpapat Tangpraphachaikul

Department of Anesthesiology, Siriraj Hospita

natpapat.t@gmail.com0814854482

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026