facial oily skin Phototherapy, Light emission diode, Red light, Blue light, Microbiota, Skin microbiology, Sebum, Oily Skin
Conditions
Interventions
Participants in this arm will receive 415 nm blue LED light therapy applied to the entire facial area. The treatment will be administered twice weekly for 4 consecutive weeks, totaling 8 sessions. Eac
Experimental Device,Active Comparator Device
415 nm Blue Light Therapy,633 nm Red Light Therapy
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
25 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Presentation of oily skin conditions, 2. Fitzpatrick skin phototypes 3 to 4
Exclusion criteria
Exclusion criteria: 1. Active inflammatory skin diseases in the treatment area, 2. Concurrent active cutaneous infections (viral, fungal, or bacterial) in the treatment area, 3. History of using topical antibiotics and non-antibiotic acne treatments within 1 month prior to study enrollment, 4. Concomitant use of oral retinoids, spironolactone or oral contraceptives within 6 months prior to study enrollment, 5. History of facial treatment with dermal fillers or biostimulators in the treatment area within 1 year prior to study enrollment, 6. History of botulinum toxin injection in the facial area within 6 months prior to study enrollment, 7. History of facial surgery within 6 months prior to study enrollment, 8. Previous treatment with lasers, Intense Pulsed Light or other phototherapies within 3 months prior to study enrollment, 9. Currently pregnant or lactating, 10. Diagnosis of photosensitive dermatosis, including Systemic Lupus Erythematosus, 11. Diagnosis of Polycystic Ovary Syndrome, 12. History of epilepsy or photosensitive seizures, 13. Presence of retinal diseases, 14. History of hypersensitivity or allergic reactions to Tegaderm patches or acrylic adhesives.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin microbiome analysis 12 weeks Next-Generation Sequencing (16S rRNA gene sequencing) | — |
Secondary
| Measure | Time frame |
|---|---|
| Sebum production 12 weeks Sebumeter,Transepidermal water loss 12 weeks Tewameter,Stratum corneum hydration 12 weeks Corneometer,Skin pH 12 weeks Skin pH meter,Pore size 12 weeks Trica 3D,Porphyrin count 12 weeks Trica 3D | — |
Countries
Thailand
Contacts
Public ContactKunlathorn Thawinprawat
Thammasat University
Outcome results
None listed