Acute Lymphoblastic Leukemia Vincristine Induced Peripheral Neuropathy Motor Function Impairment Activities of Daily Living Limitation Acute Lymphoblastic Leukemia Vincristine Induced Peripheral Neuropathy
Conditions
Interventions
Participants received a structured stress ball exercise program in addition to usual care.,Participants received usual care according to the hospital standard protocol without the stress ball exercise
Stress Ball Exercise,Usual Care
Sponsors
Faculty of Nursing, Universitas Indonesia
Eligibility
Sex/Gender
All
Age
5 Years to 16 Years
Inclusion criteria
Inclusion criteria: 1. Children diagnosed with B cell or T cell Acute Lymphoblastic Leukemia ALL 2. Received a cumulative vincristine dose of at least 6 mg per m2 3. Inpatients or outpatients with stable clinical conditions and age appropriate vital signs within normal limits 4. Able to understand and follow study instructions 5. Written informed consent obtained from parents or legal guardians and child assent when appropriate
Exclusion criteria
Exclusion criteria: 1. Peripheral neuropathy caused by conditions other than chemotherapy such as diabetes mellitus neurological disorders or nerve injury 2. Severe cardiovascular pulmonary neurological musculoskeletal cognitive or emotional disorders that may interfere with participation in the intervention or outcome assessments 3. Any medical condition judged by the investigator to make participation unsafe or affect study outcomes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vincristine induced peripheral neuropathy Baseline before intervention and 4 weeks after intervention Pediatric Chemotherapy Induced Neuropathy (PCIN) | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor function Baseline before intervention and 4 weeks after intervention Timed Up and Go (TUG), Hand Grip Strength, Nine Hole Peg Test (NHPT),Activities of daily living Baseline before intervention and 4 weeks after intervention Modified Barthel Index | — |
Countries
Indonesia
Contacts
Public ContactDesti Muslimah
Faculty of Nursing Universitas Indonesia
Outcome results
None listed