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Evaluation of palatal wound healing and post operative pain following palatal graft harvesting: comparing conventional techniques versus band-aid with Er,Cr YSGG laser- A pilot study

Evaluation of palatal wound healing and post operative pain following palatal graft harvesting: comparing conventional techniques versus band-aid with Er,Cr YSGG laser- A pilot study

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260708001
Enrollment
30
Registered
2026-07-08
Start date
2025-04-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival recession, Insufficient keratinized gingiva, Peri implant soft tissue deficiency Gingival Recession, Periodontal Plastic Surgery, Free Gingival Graft, Connective Tissue Graft, Wound Healing, Lasers, Erbium Chromium Yttrium Scandium Gallium Garnet Laser, Pain, Postoperative, Biomarkers, Hydrogen Peroxide, Intraoral Scanners

Interventions

The palatal donor site will receive Er,Cr YSGG laser treatment in Band Aid mode using the WaterLase MD system. Laser settings are wavelength 2780 nm, output power 0.5 W, frequency 20 Hz ,Air 20 percen
Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery
Er,Cr YSGG laser assisted palatal wound management,Conventional palatal wound management

Sponsors

Faculty of dentistry, thammasat university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Adult patients (age 20-65 years). 2. Good general health (ASA 1, 2) and not a contraindication for minor surgery. 3. No history of mucogingival surgery on the palatal area. 4. No systemic antibiotics taken for at least 6 months before the study.

Exclusion criteria

Exclusion criteria: 1. History of periodontal disease 2. Patients with poor oral hygiene, low cooperation, smoking habit 3. Patients who are unsuitable for laser therapy, such as those with pacemakers, untreated infections, or the presence of nearby metallic restorations or dental implants. 4. Pregnancy or lactation during the study period.

Design outcomes

Primary

MeasureTime frame
Remaining palatal wound area Baseline, Immediately after surgery, Days 7, 14, 21, and 30 after surgery serial intraoral scans acquired using a TRIOS 5 (3Shape, Copenhagen, Denmark) and quantified by three-dimensional superimposition and surface area analysis using Geomagic Control X software.,Wound epithelialization Baseline, Immediately after surgery, Days 7, 14, 21, and 30 after surgery 3% hydrogen peroxide test by evaluating the presence or absence of oxygen bubble formation on the wound surface.

Secondary

MeasureTime frame
VAS score Immediately after surgery, Days 1, 2, 3, 7, 14, 21, and 30 after surgery Visual Analog Scale, 0 to 10 scale,NSAID intake Immediately after surgery, Days 1, 2, 3, 7, 14, 21, and 30 after surgery number of NSAID intake after surgery,Palatal wound fluid biomarkers Days 3 and 7 after surgery Palatal wound fluid biomarkers concentrations, measured using ELISA and reported in pg/mL

Countries

Thailand

Contacts

Public ContactBorvornwut Buranawat

Thammasat University

premolarz@yahoo.com025644440

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026