Gingival recession, Insufficient keratinized gingiva, Peri implant soft tissue deficiency Gingival Recession, Periodontal Plastic Surgery, Free Gingival Graft, Connective Tissue Graft, Wound Healing, Lasers, Erbium Chromium Yttrium Scandium Gallium Garnet Laser, Pain, Postoperative, Biomarkers, Hydrogen Peroxide, Intraoral Scanners
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients (age 20-65 years). 2. Good general health (ASA 1, 2) and not a contraindication for minor surgery. 3. No history of mucogingival surgery on the palatal area. 4. No systemic antibiotics taken for at least 6 months before the study.
Exclusion criteria
Exclusion criteria: 1. History of periodontal disease 2. Patients with poor oral hygiene, low cooperation, smoking habit 3. Patients who are unsuitable for laser therapy, such as those with pacemakers, untreated infections, or the presence of nearby metallic restorations or dental implants. 4. Pregnancy or lactation during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remaining palatal wound area Baseline, Immediately after surgery, Days 7, 14, 21, and 30 after surgery serial intraoral scans acquired using a TRIOS 5 (3Shape, Copenhagen, Denmark) and quantified by three-dimensional superimposition and surface area analysis using Geomagic Control X software.,Wound epithelialization Baseline, Immediately after surgery, Days 7, 14, 21, and 30 after surgery 3% hydrogen peroxide test by evaluating the presence or absence of oxygen bubble formation on the wound surface. | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score Immediately after surgery, Days 1, 2, 3, 7, 14, 21, and 30 after surgery Visual Analog Scale, 0 to 10 scale,NSAID intake Immediately after surgery, Days 1, 2, 3, 7, 14, 21, and 30 after surgery number of NSAID intake after surgery,Palatal wound fluid biomarkers Days 3 and 7 after surgery Palatal wound fluid biomarkers concentrations, measured using ELISA and reported in pg/mL | — |
Countries
Thailand
Contacts
Thammasat University