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The Impact of Early Life Vitamin D Deficiency on Respiratory Morbidity and Lung Function in Very Preterm Infants at pre-school age

The Impact of Early Life Vitamin D Deficiency on Respiratory Morbidity and Lung Function in Very Preterm Infants at pre-school age

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20260703009
Enrollment
114
Registered
2026-07-03
Start date
2026-04-26
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin D deficiency, reactive airway disease, asthma Vitamin D deficiency, reactive airway disease, asthma

Interventions

Cord blood vitamin D below twelve nanogram per mL,Cord blood vitamin D between twelve and thirty nanogram per mL
Screening,Screening
Severe vitamin D deficiency,Mild to moderate vitamin D deficiency

Sponsors

Routine to research unit (R2R), Siriraj hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 5 Years

Inclusion criteria

Inclusion criteria: 1. Preterm infants GA < 32 weeks or BW < 1,500 grams who accomplished in project Si 176/2023 and age above 3 years. 2. Parents can communicate with Thai language or has translator who can speak Thai.

Exclusion criteria

Exclusion criteria: 1. Respiratory tract infection 2. Recent brain, thoracic or abdominal surgery within 4 weeks 3. Oral ulcer that interrupt pulmonary function test 4. Cannot recruit from telephone interview

Design outcomes

Primary

MeasureTime frame
Reactive airway disease when the patient reach age 3 years Impulse oscillometry

Secondary

MeasureTime frame
Lung function test when the patient reach age 3 years Impulse Oscillatory ,Growth trajectory when the patient reach age 3 years Growth chart

Countries

Thailand

Contacts

Public ContactPunnanee Wutthigate

Department of Pediatrics, Faculty of Medicine, Siriraj Hospital

punnanee.wut@mahidol.ac.th0659400902

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026