Ultrasound mapping of facial blood vessels before filler injection

Facial vascular mapping by ultrasound for safe sharp-needle filler injection: A Cross-sectional Study of vascular locations at the temple, zygoma, nasolabial fold, and chin

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20260702011

Enrollment

Registered

2026-07-02

Start date

2025-12-29

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Facial vascular anatomy for safe hyaluronic acid filler injection Facial vascular mapping

Interventions

Healthy adults aged 18 to 70 years undergoing a single high-frequency duplex ultrasound examination for facial vascular mapping.

Other

Healthy participants

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 70 years. 2. In good general health. 3. Willing to participate in the study and provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. History of head or neck surgery that may alter vascular anatomy or interfere with ultrasound visualization. 2. History of facial filler or biostimulator injection within the past 12 months.

Design outcomes

Primary

Measure	Time frame
Mean depth of the facial artery at the canine fossa Single study visit (baseline) Measured from the skin surface using high-frequency duplex ultrasound (Clarius L20 HD3) and recorded in millimeters (mm).	—

Secondary

Measure	Time frame
Anatomical location of the deep temporal artery Single study visit (baseline) Distance from the temporal crest measured using high-frequency duplex ultrasound and recorded in millimeters (mm).,Anatomical location of the zygomaticofacial artery Single study visit (baseline) Distance from the lateral canthus measured using high-frequency duplex ultrasound and recorded in millimeters (mm).,Anatomical location of the ascending mental artery Single study visit (baseline) Horizontal distance from the midline measured using high-frequency duplex ultrasound and recorded in millimeters (mm).,Vessel diameter Single study visit (baseline) Vessel diameter measured using high-frequency duplex ultrasound and recorded in millimeters (mm).,Association between facial artery depth and participant characteristics Single study visit (baseline) Statistical analysis of the association between facial artery depth and participant characteristics, including age, sex, and body mass index.	—

Measure

Time frame

Anatomical location of the deep temporal artery Single study visit (baseline) Distance from the temporal crest measured using high-frequency duplex ultrasound and recorded in millimeters (mm).,Anatomical location of the zygomaticofacial artery Single study visit (baseline) Distance from the lateral canthus measured using high-frequency duplex ultrasound and recorded in millimeters (mm).,Anatomical location of the ascending mental artery Single study visit (baseline) Horizontal distance from the midline measured using high-frequency duplex ultrasound and recorded in millimeters (mm).,Vessel diameter Single study visit (baseline) Vessel diameter measured using high-frequency duplex ultrasound and recorded in millimeters (mm).,Association between facial artery depth and participant characteristics Single study visit (baseline) Statistical analysis of the association between facial artery depth and participant characteristics, including age, sex, and body mass index.

—

Countries

Thailand

Contacts

Public ContactNatthachat Jurairattanaporn

Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University

natthachat.j.md@gmail.com0626425261

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026