Partially edentulous adults (20 to 65 years, ASA 1-2) with submerged osseointegrated dental implants Stage II abutment connection surgery peri-implant mucosal healing early postoperative inflammation marginal bone response. Dental Implants Osseointegration Lasers Oral Surgical Procedures Oral Mucosa Wound Healing Transforming Growth Factor beta Matrix Metalloproteinase Vascular Endothelial Growth Factor A Alveolar Bone Loss Treatment Outcome Follow-Up Studies Randomized Controlled Trial
Conditions
Interventions
For test group 15 participants, Er, Cr YSGG laser-assisted ablation. Soft
tissue overlying the submerged implant was ablated using
WaterLase iPlus with an MZ6 tip in non-contact
mode perpendicular
analgesics
as needed
Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery
test group,control group
Sponsors
faculty of dentistry, thammasat university
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1 Adult patients (age 20-65 years) 2 Good general health (ASA 1, 2) and not a contraindication for minor surgery. 3 Patient with a dental implant in any area of the mandible or maxilla anterior, premolar, and molar. 4 Patients who indicated the abutment connection stage in dental implant surgery. 5 Patients with implant fixtures (IS-III active, Neobiotech Co. Ltd., Seoul, Korea; Roxolid SLA Straumann Co. Ltd., Switzerland; Helix GM Neodent Straumann Co. Ltd., Switzerland; and BL RC tapered OKTAGON, Meisinger Co. Ltd., Germany) with a diameter more than or equal to 4.0 mm and a length more than 7.0 mm. 6 Patients undergoing implant placement with or without concurrent guided bone regeneration (GBR). 7 Patients who have more than 20 natural teeth. 8 No smoking or smoking history less than 10 cigarettes per day.? 9 Patients with 2 mm width of keratinized mucosa around dental implants and 2 mm in thickness in both horizontal and vertical dimensions.
Exclusion criteria
Exclusion criteria: 1) Presence of relevant medical conditions: Patients with bone disease, osteoporosis, uncontrolled diabetes mellitus, unstable or life-threatening conditions, or those requiring antibiotic prophylaxis. 2) Systemic condition that may affect periodontal disease susceptibility and/or treatment, i.e., diabetes mellitus, history of malignancy, radiotherapy, or chemotherapy for malignancy in the past 5 years. 3) Patients with medication of drugs influencing the bone metabolism or using bisphosphonates. 4) Pregnancy or lactation during the study period. 5) Patients with primary bone augmentation before dental implant placement. 6) Patients who are diagnosed with early peri-implantitis. 7) Patients with active infection or pathologic lesions prior to operation. 8) Abutment connection stage surgery requires additional treatment such as osteotomy, connective tissue graft, or free gingival graft. 9) The dental implant fixture has been inserted deeper than 1 mm. 10) Poor oral hygiene. 11) Patients who cannot control periodontitis (PI < 20%, BI < 10%, remaining PD < 5 mm) or patients who have been treated with supportive periodontal therapy (SPT) for 1 year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing response 7,14,30 days after surgery Peri-implant crevicular fluid biomarker concentrations, measured using ELISA and reported in pg/mL | — |
Secondary
| Measure | Time frame |
|---|---|
| soft tissue analysis 7,14,30 days after surgery Three-dimensional intraoral scan analysis using STL superimposition; mean deviation, RMS, and SD reported in millimeters (mm),VAS score 7,14,30 days after surgery Visual Analog Scale, 0 to 10 scale,healing index 7,14,30 days after surgery Clinical healing index score assessed by visual clinical examination,bleeding on probing 7,14,30 days after surgery Presence or absence of bleeding after probing using a periodontal probe; recorded as Yes/No,Time Efficiency 7,14,30 days after surgery Surgical duration measured from the first incision or laser contact to completion of healing abutment connection; reported in minutes,Marginal bone level 7,14,30 days after surgery Periapical radiographic measurement of marginal bone level using image analysis software; reported in millimeters (mm),modified gingival index 7,14,30 days after surgery Modified gingival index score assessed by clinical examination,bleeding score 7,14,30 days after surgery Intraoperative bleeding assessed using a clinical bleeding score, 01,2,3 scale | — |
Countries
Thailand
Contacts
Public ContactBorvornwut Buranawat
Thammasat University
Outcome results
None listed