Energy expenditure and cardiopulmonary physiological response during simple exercises in Healthy subject: a pre-clinical validation

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260629006

Enrollment

Registered

2026-06-29

Start date

2023-08-07

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

An alternative exercise approach for the healthy population employing ISMT, IHKT, ISWT, and IAST across three age cohorts (18-39, 40-59, 60-79 years) healthy population, alternative exercise

Interventions

The standard intervention is an Incremental Treadmill Test using the Modified Bruce Protocol on a motorized treadmill. Participants undergo a progressive, multi-stage workload protocol where the speed

Active Comparator Other,Active Comparator Other,Active Comparator Other,Active Comparator Other,Active Comparator Other

Treadmill ,Incremental High Knee Walking (IHKT),Incremental Spot Walking (ISWT),Incremental Spot Marching (ISMT),Incremental Arm Swing (IAST)

Eligibility

Sex/Gender

All

Age

18 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1. Healthy volunteers aged 18 to 79 years 2. normal body mass index (18.5-24.9 kg/m2) 3. willingness to provide informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria include 1. individuals with history of chronic obstructive pulmonary disease, pneumonia, cardiovascular diseases, asthma, cancer, or smoking at least 10 pack-years. 2.Persons with musculoskeletal conditions like joint pain or limb fractures, neurological disorders such as stroke, spinal cord injury, or traumatic brain injury are also excluded 3. Other criteria comprise resting hypotension (below 90/60 mmHg), resting hypertension (above 140 mmHg), inability to coordinate marching or swinging movements, or inability to complete the full 14-day study period.

Design outcomes

Primary

Measure	Time frame
Metabolic variable measurement resting phase, exercise phase, recovery phase Oxygen consumption, carbon dioxide out put	—

Secondary

Measure	Time frame
cardiovascular variable measurement resting phase, exercise phase, recovery phase %age-predicted percent heart rate maximum, percent of heart rate reserve, heart rate, blood pressure,pulmonary variable measurement resting phase, exercise phase, recovery phase Oxygen saturation, tidal volume, minute ventilation, respiratory rate, end-carbon dioxide,Perceptual variable measurement resting phase, exercise phase, recovery phase rate perceived of breathlessness and exertion, rating of arm fatigue, rating of leg fatigue	—

Measure

Time frame

cardiovascular variable measurement resting phase, exercise phase, recovery phase %age-predicted percent heart rate maximum, percent of heart rate reserve, heart rate, blood pressure,pulmonary variable measurement resting phase, exercise phase, recovery phase Oxygen saturation, tidal volume, minute ventilation, respiratory rate, end-carbon dioxide,Perceptual variable measurement resting phase, exercise phase, recovery phase rate perceived of breathlessness and exertion, rating of arm fatigue, rating of leg fatigue

—

Countries

Thailand

Contacts

Public ContactChatcahi Phimphasak

Assistant professor

chatphi@kku.ac.th0826451964

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026