Visible light protection factor of Oryza Sativa Tinted sunscreen, Visible light protection, Hyperpigmentation, Individual Typology Angle, Ultraviolet A1
Conditions
Interventions
TINTED TONE UP UV SUNSCREEN SPF50 PA+++ (SKY020-03) - light shade tinted sunscreen,TINTED TONE UP UV SUNSCREEN SPF50 PA+++ (SKY021-04)-light shade tinted sunscreen,TINTED TONE UP UV SUNSCREEN SPF50 PA
Sponsors
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Healthy volunteers aged 18 years or older 2. Having tan, brown, or dark skin types, evaluated using an Individual Typology Angle (ITA) value ranging from 10 to -40 measured by a Colorimeter at the lower back (the designated test site).Able to avoid sun exposure on the back area throughout the duration of the research study. - Able to lie in a prone position continuously for at least 1 hour without any respiratory issues.
Exclusion criteria
Exclusion criteria: 1. Individuals with a history of sunbathing or intense sun exposure on the back within 1 month prior to the study. 2. Individuals with a history of using photosensitizing agents, immunosuppressants, or anti-inflammatory drugs within 1 month prior to the study. 3. Individuals with a history of laser treatment or artificial UV phototherapy on the back within 6 months prior to the study. 4. Individuals with plans to undergo any medical treatments or procedures on the back during the study period that could affect the interpretation of the results. 5. Individuals with a history of photosensitivity disorders, photodermatoses, skin cancer, or skin diseases exacerbated by sunlight. 6. Individuals with open wounds, skin infections, or active rashes/dermatitis on the back area. 7. Individuals with underlying medical conditions that affect the immune system. 8. Individuals who have used medications affecting the immune system within 3 weeks prior to the study. 9. Individuals who are currently pregnant, breastfeeding, or less than 3 months postpartum Individuals with a known history of allergy to sunscreen ingredients. 10. Individuals who are unable to read or communicate effectively in the Thai language.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ITA by colorimeter baseline, 15 min, day1, day2, day3, day4, day7 Colorimeter,Reaction after 24 hr occlusive patch test day1, day2 dermatologist according to the Cosmetic, Toiletry, and Fragrance Association (CTFA) guideline. | — |
Secondary
| Measure | Time frame |
|---|---|
| IGA for hyperpigmentation baseline, 15 min, day1, day2, day3, day4, day7 physician | — |
Countries
Thailand
Contacts
Public ContactWoraphong Manuskiatti
Faculty of medicine, Siriraj hospital
Outcome results
None listed