bladder discomfort catheter-related bladder discomfort (CRBD)
Conditions
Interventions
intravenous nefopam 20 mg diluted in 100 mL normal saline,100 mL normal saline alone
Experimental Drug,Placebo Comparator Drug
N group,C group
Sponsors
Ratchadapisek Research Funds
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Female patients aged 18-80 years 2. American Society of Anesthesiologists physical status I-III 3. Scheduled for elective laparoscopic gynecologic surgery requiring urinary catheterization for at least 24 hours
Exclusion criteria
Exclusion criteria: 1. bladder outflow obstruction or overactive bladder 2. epilepsy or seizure disorders 3. severe cardiovascular, hepatic, or renal disease 4. current use of selective serotonin reuptake inhibitors, monoamine oxidase inhibitors, or tricyclic antidepressants 5. pregnancy or lactation 7. closed-angle glaucoma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of CRBD upon admission to the post-anesthesia care unit (PACU) upon PACU admission incidence of CRBD | — |
Secondary
| Measure | Time frame |
|---|---|
| CRBD incidence at 1, 2, 6, and 24 hours at 1, 2, 6, and 24 hours postoperatively incidence of CRBD,postoperative pain scores at 1, 2, 6, and 24 hours postoperatively NRS,24-hour morphine consumption 24 hours postoperatively morphine accumulative dose | — |
Countries
Thailand
Contacts
Public ContactNalin Chokengarmwong
King Chulalongkorn Memorial Hospital
Outcome results
None listed