Mild Cognitive Impairment (MCI) often precedes dementia, with systemic inflammation playing a potential role in neurodegeneration. Elevated high-sensitivity C-reactive protein (hs-CRP) is associated with cognitive decline Kao-TA Kao-Ten exercise mild cognitive impairment cognitive function mind-bodyexercise MoCA TMSE
Conditions
Interventions
the Kao-TA Kao-Ten exercise
program. This mind-body intervention involved rhythmic physical movements performed on a
nine-square dance board, with stepping patterns corresponding to letters of the E
Experimental Other,No Intervention No treatment
Sponsors
Chulabhorn International College of Medicine, Thammasat University, Thailand
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.who had been diagnosed with MCI by a neurologist 2. TMSE scores of 24 and MoCA Thai scores of 26 3. able to communicate fluently in Thai and remained functionally independent.
Exclusion criteria
Exclusion criteria: 1.suspected dementia (TMSE < 23 and MoCA < 22) 2.severe medical conditions limiting physical activity, neurological or psychiatric disorders affecting cognition 3.significant sensory or mobility impairment 4. concurrent participation in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment at 12 weeks after end of the intervention Montreal Cognitive Assessment score,Thai Mental State Examination at 12 weeks after end of the intervention Thai Mental State Examination score | — |
Secondary
| Measure | Time frame |
|---|---|
| Hs-CRP Protein at 12 weeks after end of the intervention measuring serum levels,Pittsburgh Sleep Quality Index at 12 weeks after end of the intervention Pittsburgh Sleep Quality Index score,The World Health Organization Quality of Life at 12 weeks after end of the intervention The World Health Organization Quality of Life score | — |
Countries
Thailand
Contacts
Public ContactParepan Naroied
Chulabhorn International College of Medicine, Thammasat University,
Outcome results
None listed