Iron deficiency anemia Iron-Deficiency Anemia Iron Dietary Supplements Ferritins Hemoglobins Fatigue
Conditions
Interventions
Participants receive oral iron supplementation containing 10 to 15 mL orally twice daily for 4 weeks to improve hemoglobin, serum ferritin, fatigue level, and oxygen saturation.,Participants receive
Oral Iron Supplementation (Organic Iron Supplement),Standard Dietary Counseling
Sponsors
Imran Ahmad Khan
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. University students aged 18 to 30 years with hemoglobin below WHO criteria 2. Participants with serum ferritin less than 30 ug/L 3. Participants with Fatigue Severity Scale score greater than or equal to 4, 4. Participants with their peripheral blood smear showing hypochromic microcytic anemia with pencil shaped red blood cells.
Exclusion criteria
Exclusion criteria: 1. Participants with severe anemia, thalassemia, sickle cell anemia 2. Participants with chronic kidney disease, chronic liver disease, malignancy, acute infection 3. Participants with inflammatory disease 4. Participants who have pregnancy 5. Lactating Females 6. Participants with recent iron therapy within the last 3 months, vitamin B12 deficiency, folate deficiency 7. Participants with gastrointestinal malabsorption disorders, known allergy to oral iron supplementation 8. Participants who were unwilling to participate were excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin Baseline and 4 weeks post intervention Measured in g/dL using automated hematology analyzer (Complete Blood Count),Serum Ferritin Baseline and 4 weeks post intervention Measured using ELISA ,Fatigue Severity Scale score Baseline and 8 weeks post intervention 9-item Fatigue Severity Scale (FSS), mean score calculated ,Oxygen Saturation Baseline and 4 weeks post intervention Measured in percentage (%) using fingertip pulse oximeter | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Symptoms of Anemia Baseline and 4 weeks post intervention tructured questionnaire assessing fatigue related symptoms such as weakness, dizziness, and poor concentration,Complete Blood Count Parameters Baseline and 4 weeks post intervention RBC count using automated hematology analyzer,Peripheral Blood Smear Morphology Baseline and 4 weeks post intervention Examination of peripheral blood smear slides using light microscopy to assess red blood cell morphology including hypochromia, microcytosis and pencil shaped red blood cells (elliptocytes),Respiration rate Baseline and 4 weeks post intervention Measured in breaths per minute using standard clinical observation method | — |
Countries
Pakistan
Contacts
Public ContactMaliha Khan
Muhammad Nawaz Sharif University of Agriculture Multan
Outcome results
None listed