Benefits and side effects of drinking a carbohydrate solution before planned cesarean delivery

Effectiveness and adverse effects of preoperative oral carbohydrate loading before elective cesarean delivery: A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260619003

Enrollment

Registered

2026-06-19

Start date

2024-12-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insulin resistance after cesarean delivery Postoperative inflammatory response Maternal discomfort during preoperative fasting Postoperative nausea and vomiting Perioperative metabolic complications Cesarean Section Insulin Resistance Inflammation Preoperative Care Carbohydrates Postoperative Nausea and Vomiting Pregnancy Gastric Emptying Spinal Anesthesia Enhanced Recovery After Surgery

Interventions

Maltodextrin 15% solution (Carberas brand): - Evening before surgery: 600 mL consumed gradually before midnight - Morning of surgery: 300 mL consumed gradually until 2 hours before scheduled surgery s

Experimental Dietary Supplement,Active Comparator Behavioral

Preoperative Oral Carbohydrate Loading,Preoperative fasting

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. aged 18 to 45 years 2. singleton pregnancy at term (gestational age from 37 weeks) 3. an American Society of Anesthesiologists (ASA) physical status of II or III 4. cesarean section under spinal anesthesia

Exclusion criteria

Exclusion criteria: 1. multiple pregnancies 2. history of gastrointestinal motility disorders (e.g., gastroesophageal reflux disease, pyloric obstruction) 3. pre-existing or gestational diabetes mellitus 4. high-risk pregnancy complications such as preeclampsia or eclampsia.

Design outcomes

Primary

Measure	Time frame
Insulin resistance Preoperative, postoperative and 24 hours post-operative Homeostasis model assessment (HOMA-IR index),Insulin resistance Preoperative, postoperative and 24 hours post-operative Quantitative insulin sensitivity check index (QUICKI index),Insulin resistance Preoperative, postoperative and 24 hours post-operative insulin blood,inflammatory respone Preoperative, postoperative and 24 hours post-operative White Blood Cell count (WBC),inflammatory respone Preoperative, postoperative and 24 hours post-operative C-Reactive Protein (CRP),inflammatory respone Preoperative, postoperative and 24 hours post-operative Procalcitonin,inflammatory respone Preoperative, 24 hours post-operative interlekin 6	—

Measure

Time frame

Insulin resistance Preoperative, postoperative and 24 hours post-operative Homeostasis model assessment (HOMA-IR index),Insulin resistance Preoperative, postoperative and 24 hours post-operative Quantitative insulin sensitivity check index (QUICKI index),Insulin resistance Preoperative, postoperative and 24 hours post-operative insulin blood,inflammatory respone Preoperative, postoperative and 24 hours post-operative White Blood Cell count (WBC),inflammatory respone Preoperative, postoperative and 24 hours post-operative C-Reactive Protein (CRP),inflammatory respone Preoperative, postoperative and 24 hours post-operative Procalcitonin,inflammatory respone Preoperative, 24 hours post-operative interlekin 6

—

Secondary

Measure	Time frame
Gastric Residual Volume Preoperative Ultrasound CSA measurement ,Hunger score Preoperative Visual Analog Scale,Thirst score Preoperative Visual Analog Scale,Dry mouth score Preoperative Visual Analog Scale,Postoperative nause and vomiting post operative, and 24h postoperative Yes/no,Apgar score postoperative 1-10,Volume/Weight preoperative Perlas formula,Volume/Weight Preoperative Roukhomovsky	—

Countries

Vietnam

Contacts

Public ContactHuynh Dang

Hanoi Obstetrics & Gynecology Hospital

huynhhmu@gmail.com84362567896

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026