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A Double-Blind Randomized Controlled Trial Comparing the Efficacy of Ginger Extract and Simethicone Using Patient-Reported Outcome Measures after Gastrointestinal Endoscopy

A Double Blind Randomized Controlled Trial Comparing the Efficacy of Ginger Extract and Simethicone Using Patient Reported Outcome Measures after Gastrointestinal Endoscopy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260605004
Enrollment
120
Registered
2026-06-05
Start date
2025-04-07
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient who need GI endoscopy. Endoscopy, Gastrointestinal

Interventions

Ginger extract before endoscopy,Simethicine before endoscopy
Experimental Drug,Active Comparator Drug
Ginger,Simethicone

Sponsors

Navamindradhiraj University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged between 18 and 70 years. 2. Patients with indications for undergoing elective gastrointestinal endoscopy (EGD, ERCP, or Colonoscopy). 3. Patients with no prior history of hypersensitivity or allergy to ginger extract or simethicone.

Exclusion criteria

Exclusion criteria: 1. Pregnant women (as determined by last menstrual period history, or a pregnancy test if pregnancy is suspected). 2. Patients with severe gastrointestinal disease or severe cardiovascular disease classified as ASA physical status class IV-V. 3. Patients with a known history of allergy or hypersensitivity to any of the components related to the study products.

Design outcomes

Primary

MeasureTime frame
Abdominal discomfort 1 hr post endoscopy Questionnaire

Secondary

MeasureTime frame
Mucosal visibility 1 hr post endoscopy Questionnaire

Countries

Thailand

Contacts

Public ContactSuphakarn Techapongsatorn

Navamindradhiraj University

suphakarn@nmu.ac.th022443282

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026