Metabolic-associated steatotic liver disease (MASLD) obesity hepatic steatosis metabolic dysfunction weight management Metabolic-associated steatotic liver disease (MASLD) obesity hepatic steatosis metabolic dysfunction Gin Dee Line
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 Adult aged 18 years or older 2 Hepatic steatosis confirmed by Fibroscan with CAP 260 dB per m or over 3 BMI 23 kg per square meter or over 4 Ability and willingness to comply with study procedures
Exclusion criteria
Exclusion criteria: 1 Other liver disease 2 Significant alcohol intake 3 DILI 4 Severe uncontrolled medical illnesses 5 Pregnancy or lactation 6 Current insulin use 7 Participation in a recent weight loss program 8 Psychiatric conditions affecting adherence
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in hepatic steatosis at Week 24 24 weeks FibroScan CAP score | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in Body weight or BMI 6 months Zepper | — |
Countries
Thailand
Contacts
Bhumibol Adulyadej Hospital