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Pilot project: the treatment of amphetamine derivatives addicted patients with herbs and Thai traditional medicine

Pilot project: the treatment of amphetamine derivatives addicted patients with herbs and Thai traditional medicine

Status
Recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260603008
Enrollment
30
Registered
2026-06-03
Start date
2024-05-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amphetamine-type stimulant (ATS) use remains a major public health challenge in Thailand. Thai traditional Medicine was used for detoxification for toxic substance but there is no record for addict patients. amphetamine-type stimulants, methamphetamine, Traditional Thai Medicine, herbal medicine, detoxification, addiction treatment

Interventions

The treatment program comprised a standardized combination of herbal medicines and supportive beverages formulated according to TTM principles.
Experimental Drug
Thai Traditional Medicine Program

Sponsors

NRCT
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Male, aged 18 to 60 years, diagnosed with amphetamine-type stimulant addiction. 2.Practicing Buddhist and able to communicate in Thai (this criterion was required due to the Dhamma-based psychosocial component of the program; its implications for generalizability are noted in the limitations). 3.Willingness to participate and complete the 10-day program. 4.Screening score more than 4 on the Ministry of Public Health Screening and Referral Form for Substance Users (Version 2), indicating substance use or dependence. 5.Negative depression screening using the 2-question test (2Q). Participants with positive 2Q results were further assessed with the 9-question test (9Q) those scoring less than 7 were eligible. Participants with 9Q scores more than 7 were administered the 8-question suicide risk assessment (8Q) and only those scoring less than 8 were included.

Exclusion criteria

Exclusion criteria: 1. History of hepatitis, cirrhosis, nephritis, or acute/chronic renal failure. 2. Severe or uncontrolled medical illness. 3. Active or uncontrolled psychiatric disorders (e.g., psychosis, acute intoxication, or suicidal/homicidal risk). 4. Known hypersensitivity to any herbal components used in the treatment.

Design outcomes

Primary

MeasureTime frame
Efficacy day0,4,9 and Month 3 Methamphetamine level in blood , urine and hair,Safety Day 0,4,9 and Month 3 Blood Chemistry

Secondary

MeasureTime frame
Quality of life Day 0,9 QOL score

Countries

Thailand

Contacts

Public ContactArunporn Itharat

Faculty of Medicine , Thammasat University

iarunporn@yahoo.com9269749

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026