Healthy patients requiring surgical removal of identical bilateral lower third molar impaction Post-op surgical removal of impacted lower third molars Combined-PRF
Conditions
Interventions
Preparation of platelet concentrate for the intervention arm. Blood collection will be similar to a routine blood test procedure from the antecubital region. A total of 20 mL of blood will be drawn fo
Experimental Procedure/Surgery,No Intervention Procedure/Surgery
Standard treatment with application of APRF plus and iPRF,Standard treatment
Sponsors
Laddawun Sununliganon
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Patients who require surgical removal of identical bilateral impacted lower third molars, 2. Health status is categorized according to the American Society of Anesthesiologists (ASA) as ASA I and ASA II, 3. No history of medication-related osteonecrosis of the jaw or previous radiotherapy in the head and neck area, 4. No drug allergies related to the study, 5. No administration of anti-inflammatory drugs, steroids, or antibiotics within two weeks before the operation, 6. No psychological disorders or mental impairments, 7. No systemic conditions that could affect metabolism and healing responses, 8. Nonsmokers or light smokers (less than 10 cigarettes per day), 9. No history of platelet disorders or use of antiplatelet or anticoagulant therapy, 10. No active inflammation or pathology associated with the impacted tooth, 11. Ability to comply with a follow-up schedule. follow-up schedule
Exclusion criteria
Exclusion criteria: Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial contour Pre-operation, 3 and 7 days post-opertion The distances on the face are defined as H1, H2, and V | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain Pre-op, 3 and 7 days post-operation Visual analog scale,Degree of mouth opening Pre-op, 3 and 7 days post-ioperation Digital caliper measured from tooth 22 to 41,Sign of inflammation Day 3 and 7 post-operation wound color (Red: Yes/No),Patients' satisfaction 7 days post-operation Visual analog scale,Quality of Life (QOL) 7 days post-operation Questionnaires: Postoperative Symptom Severity (PoSSe) scale | — |
Countries
Thailand
Contacts
Public ContactLaddawun Sununliganon
Rangsit University
Outcome results
None listed