MASLD, MASH, Obesity MASLD MASH Obesity Weight Loss AI Chatbot
Conditions
Interventions
1.The patient LINE application will be connected to the LLM system API at the first physician visit (week 0). At the initial setup, personal information will be entered, including underlying diseases,
LLM Weight Management (LWM),In-person Management standard care (IPM)
Sponsors
The Gastrointestinal association of Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Adults aged 18 to 65 years 2.Diagnosed with MASLD or MASH based on imaging or VCTE according to AASLD/APASL criteria 3.BMI equal or more than 25 kg/m 4.Provide informed consent to participate in the study 5.Able to read, write, and communicate clearly in Thai, and have access to a smartphone or the internet (LWM group)
Exclusion criteria
Exclusion criteria: 1.Other liver diseases, including HBV, HCV, autoimmune liver disease, or significant alcohol consumption, defined as an average intake of >30 g/day in men and >20 g/day in women 2.Cirrhosis or METAVIR F4 fibrosis 3.HCC at any stage 4.Planned initiation of any new weight-loss medication during the study period 5.Severe medical illness or psychiatric disorder that would interfere with study participation 6.Pregnancy or breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of participants who achieve more than or equal to 5% weight loss from baseline body weight at 6 months 6 months Weighing | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage change in body weight over time 2 4 6 months Weighing,Changes in CAP and LSM 6 months VCTE ,Reduction in ALT/AST levels 2 4 6 months Blood test (LFT),Changes in HbA1c, FPG, lipid profile, and blood pressure 2 4 6 months Blood tests,Adherence rate, including LLM usage rate and clinic attendance rate 2 4 6 months Case record form at visit ,Satisfaction 6 months Questionnaire | — |
Countries
Thailand
Contacts
Public ContactPanlert Prasanwon
Phramongkutklao hospital
Outcome results
None listed