Development and production of ready-to-use, texture modified-blenderized diet from rice and Thai agricultural raw materials for commercial use (Year 2): Clinical research on postprandial glucose, insulin, and GLP-1

Postprandial Metabolic Responses to Texture Modified- Blenderized Diets in Thai Patients with Type 2 Diabetes

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260601029

Enrollment

Registered

2026-06-01

Start date

2025-07-30

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thai T2DM patients aged 30-60 years. Blenderized diet, Postprandial metabolic responses

Interventions

A vegetarian modified blenderized diet provides 300 kcal,A low-GI modified blenderized diet provides 300 kcal ,A commercial blenderized diet provides 300 kcal

Experimental Dietary Supplement,Experimental Dietary Supplement,Active Comparator Dietary Supplement

Vegetarian modified blenderized diet,Low-GI modified blenderized diet,Commercial blenderized diet

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Thai patients with T2DM who had been diagnosed for less than or equal to 12 years 2. Fasting plasma glucose less than or equal to 180 mg/dL 3. Had BMI of 18.5-34.9 kg/m2 4. Had stable oral hypoglycemic agents (excluding alpha-glucosidase inhibitors) for at least 3 months 5. Not being pregnant or lactating women

Exclusion criteria

Exclusion criteria: 1. Use glucose-lowering injection (insulin, GLP-1 analog) 2. Diagnosed with chronic liver disease, chronic kidney disease, or thyroid disease 3. Has undergone gastrointestinal surgery 4. Taking medications that affect glucose metabolism (e.g., steroids, antipsychotics, immunosuppressants, protease inhibitors, contraceptive drugs, or glucose-lowering medications) 5. Taking medications that affect nutrient digestion and absorption (e.g., pancreatic enzymes, laxatives, or anticonvulsants) 6. Taking dietary or herbal supplements (e.g., whey protein, dietary fiber, chromium, bitter melon, East Indian screw tree, and Siamese cassia) within the past 1 month 7. Regular drinking alcoholic beverages 8. Known allergies to ingredients in the developed formulas (e.g., soy protein, milk protein, pea protein, Wolffia globosa, chicken, black sesame seeds, jasmine rice, perilla oil, rice bran oil, egg, pumpkin) 9. Currently participating in a weight loss program (e.g., calorie restriction, time-restricted feeding)

Design outcomes

Primary

Measure	Time frame
Incremental area under the curve (iAUC) for blood glucose 0-240 minutes Enzymatic method,Incremental area under the curve (iAUC) for serum insulin 0-240 minutes electrochemiluminescence immunoassay (ECLIA),Incremental area under the curve (iAUC) for plasma GLP-1 0-240 minutes enzyme-linked immunosorbent assay (ELISA)	—

Secondary

Measure	Time frame
N/A N/A N/A	—

Countries

Thailand

Contacts

Public ContactThunnalin Winuprasith

Institute of Nutrition, Mahidol University

thunnalin.win@mahidol.ac.th028002380

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Jun 29, 2026