Skip to content

Development and Validation of a Clinical Prediction Score for Streptokinase Failure in patients with ST-Segment Elevation Myocardial Infarction : A Retrospective cohort study in Sisaket Hospital (SK-FAILED SCORE)

Development and Validation of a Clinical Prediction Score for Streptokinase Failure in patients with ST-Segment Elevation Myocardial Infarction : A Retrospective cohort study in Sisaket Hospital (SK-FAILED SCORE)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20260601024
Enrollment
167
Registered
2026-06-01
Start date
2024-03-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ST-segment Elevation Myocardial Infarction Thrombolytic Failure STEMI Streptokinase Predictive score Thrombolysis Treatment Failure

Interventions

Patients diagnosed with ST segment Elevation Myocardial Infarction who presented within twelve hours of symptom onset and were treated with a full dose of intravenous Streptokinase at Sisaket Hospit
Diagnostic
STEMI patients receiving Streptokinase.

Sponsors

Sisaket hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with ST-Segment Elevation Myocardial Infarction (STEMI) 2.Patients presenting with chest pain at the hospital within 12 hours of symptom onset 3.Patients with indications for and who received a full dose of 1.5 million units of Streptokinase (SK) intravenously at community hospitals in Sisaket province or at Sisaket Hospital 4.Patients referred to Sisaket Hospital for Coronary Angiography 5.Patients with complete medical records and data

Exclusion criteria

Exclusion criteria: 1.Patients with a history of Coronary Artery Bypass Grafting (Previous CABG) due to the complexity of collateral or graft flow affecting standard assessment 2.Patients with Left Bundle Branch Block (LBBB) on electrocardiogram due to limitations in ST-segment interpretation 3.Patients who declined or refused to undergo Coronary Angiography

Design outcomes

Primary

MeasureTime frame
Thrombolysis failure in STEMI patients Within 90 minutes after Streptokinase administration and during Coronary Angiography (CAG) Clinical assessment (ST-segment resolution less than 50%) and CAG results (TIMI flow grade less than 3 in the culprit artery)

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Thailand

Contacts

Public ContactJindaporn Chaiyakhot

Sisaket hospital

joyjindaporn55@gmail.com0925436940

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026