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Effectiveness of the 'Frailty Zero' Application on Physical Function Rehabilitation in Pre-frail Older Adults: A randomized controlled non-inferiority trial

Effectiveness of the 'Frailty Zero' Application on Physical Function Rehabilitation in Pre-frail Older Adults: A randomized controlled non-inferiority trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260523012
Enrollment
80
Registered
2026-05-23
Start date
2026-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Community-dwelling older adults with a pre-frail condition Older Adults, Frail

Interventions

This group will perform the exercise regimen independently at home, guided entirely by the content provided within the Mobile Application. The primary role of the physical therapist and medical staff
Frailty Zero application-based treatment,Community advised-based treatment

Sponsors

Faculty of Associated Medical Sciences, Chiang Mai University
Lead Sponsor
Busaba Chuatrakoon,Puntarik Kaewtep,Supatcha Konghakote
Collaborator

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Having a prefrailty condition by Fried Phenotype assessment. 2. Willingness to participate and provide informed consent to the study, and commitment to remain in the study until its completion. 3. Possession of a smartphone with the ability to access the Line Official Account application and a stable wireless internet network. 4. Ability to communicate effectively and read and write in the Thai language. 5. Ability to walk independently without assistance.

Exclusion criteria

Exclusion criteria: 1. Individuals with uncorrected vision problems that interfere with smartphone use or participation in physical activities. 2. Individuals with cognitive impairment or severe language comprehension deficits that prevent them from understanding study procedures or following application instructions. 3. Individuals with medical conditions that are contraindications or obstacles to exercise, such as uncontrolled hypertension, severe cardiovascular disease, recent stroke or severe cerebrovascular disease, Parkinson's disease or other neurological conditions that severely impair balance and mobility. 4. Individuals with physical disability or injury (e.g., recent fracture or severe joint pain) that significantly limit arm or leg movement, making them unable to perform the prescribed exercises. 5. Inability to adhere to the study procedures and the prescribed exercise regimen.

Design outcomes

Primary

MeasureTime frame
Physical function (Muscle strength, Endurance, Flexibility, Balance and mobility) Baseline (pre-intervention) and after 3 months of program completion (post-intervention) the senior fitness test components (the biceps curl test, the 30-second chair stand test, the two-minute step test, the back scratch test, the chair sit-and-reach test, the 2.45-meter up-and-go test),Frailty status Baseline (pre-intervention) and after 3 months of program completion (post-intervention) the conversion rate (determined using the Fried Frailty Phenotype)

Secondary

MeasureTime frame
Quality of life after 3 months of program completion (post-intervention) WHOQOL-OLD,Adherence/compliance after 3 months of program completion (post-intervention) The rate of completion of the prescribed 24 exercise sessions.

Countries

Thailand

Contacts

Public ContactMunlika Sremakaew

the Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University

munlika.s@cmu.ac.th053949250

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026