Effect of high-flow nasal cannula on diameter and collapsibility index of IVC in emergency patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260523008

Enrollment

Registered

2026-05-23

Start date

2026-05-11

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adults (age over 18 years old) with acute respiratory failure from any cause High-flow nasal cannula, IVC diameter, IVC collapsibility index, Point-of-care ultrasound OR POCUS,

Interventions

Patients with respiratory failure receiving high-flow nasal cannula (HFNC) therapy at different flow rates (30, 40, 50, and 60 L/min).

Experimental Device

Acute respiratory failure

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age more than 18 years old, 2.Patients diagnosed with acute respiratory failure or shock (defined as systolic blood pressure below 90 mmHg or mean arterial pressure below 65 mmHg, accompanied by signs of inadequate peripheral perfusion such as cold extremities), from any cause

Exclusion criteria

Exclusion criteria: 1.Pregnancy, 2.Patients who require immediate endotracheal intubation or non-invasive ventilation (NIV) upon arrival to the emergency department (such as decreased level of consciousness, coma, or severe air hunger) Patients with severe hypoxemic respiratory failure , 3.Patients with life-threatening cardiac arrhythmias (such as sinus node dysfunction or atrioventricular block with heart rate below 50 times per minutes, supraventricular tachycardia , or ventricular tachycardia ), 4.Patients with acute coronary syndrome that need emergency intervention, 5.Situations in which performing ultrasound would delay essential treatment (such as patients requiring urgent endotracheal intubation) Patients with known pulmonary hypertension, tricuspid regurgitation (TR), cardiac tamponade, pulmonary embolism, or acute respiratory distress syndrome (ARDS), 6.Patients with cardiac arrest, 7.Patients unable to tolerate the supine position for ultrasound examination.

Design outcomes

Primary

Measure	Time frame
IVC size and collapsibility index EVERY 5 MINUTES measure IVC index at HFNC rate 30, 40, 50, and 60 litre/min	—

Secondary

Measure	Time frame
disease categories subgroup EVERY 5 MINUTES measure IVC index at HFNC rate 30, 40, 50, and 60 litre/min	—

Countries

Thailand

Contacts

Public ContactApichaya Monsomboon

Deparment of Emergency Medicine, Faculty of Medicine Siriraj Hospital, Mahidol university

apich_ja@yahoo.com024199216

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026