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Effects of Reformulated Reduced-Sodium Seasoning with Thai Herbs and Chaya Leaves on Salty Taste Recognition Threshold and Urinary Sodium Excretion in Early-Stage Chronic Kidney Disease

A Community-Based Controlled Clinical Trial to Evaluate the Effects of Reformulated Reduced-Sodium Seasoning with Chaya Leaf on Salty Taste Recognition Threshold and Urinary Sodium Excretion in Patients with Early-Stage Chronic Kidney Disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260520005
Enrollment
42
Registered
2026-05-20
Start date
2020-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease Hypertension High sodium intake Chronic kidney disease Sodium intake Salt taste Urinary sodium excretion Blood pressure Dietary intervention Randomized controlled trial Community based intervention

Interventions

Participants receive a reformulated reduced sodium seasoning with Chaya leaf and are instructed to use it in daily household cooking instead of regular seasoning for eight weeks. The product contains
Reduced sodium seasoning with Chaya leaf,Reduced sodium seasoning without Chaya leaf

Sponsors

Khon Kaen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with chronic kidney disease stages 1 to 3 2.Age between 18 and 60 years 3.Able to prepare meals at home 4.Regular use of seasoning in household cooking 5.Willing to comply with study procedures and provide informed consent

Exclusion criteria

Exclusion criteria: 1.Chronic kidney disease stage 4 or 5 2.History of major cardiovascular events such as stroke 3.Severe systemic illness 4.Known taste or tongue disorders 5.Alcohol dependence 6.Unable to follow study procedures

Design outcomes

Primary

MeasureTime frame
Salty taste recognition threshold Baseline week four and week eight Measured using standardized salt taste test

Secondary

MeasureTime frame
Urinary sodium excretion Baseline week four and week eight Estimated from spot urine using validated equation,Blood pressure Baseline week four and week eight Measured using standard sphygmomanometer,Kidney function Baseline week four and week eight Estimated glomerular filtration rate from serum creatinine,Dietary sodium intake Baseline week four and week eight Assessed using dietary recall method

Countries

Thailand

Contacts

Public ContactJuthamas Kongphapa

Kasetsart University

juthamas.kon@ku.th0945218642

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026