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Effect of Preoperative Oral Carbohydrate Loading Versus Overnight Fasting on Preoperative Anxiety in Women Undergoing Elective Cesarean Section: A Randomized Controlled Trial

Effect of Preoperative Oral Carbohydrate Loading Versus Overnight Fasting on Preoperative Anxiety in Women Undergoing Elective Cesarean Section: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260519002
Enrollment
60
Registered
2026-05-19
Start date
2026-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative fasting and maternal discomfort in women undergoing elective cesarean section Cesarean Section, Preoperative Fasting, Carbohydrate Loading, Preoperative Anxiety, Time to First Flatus, ERAS

Interventions

100% apple juice 300 mL administered orally 2 hours before scheduled elective cesarean section under spinal anesthesia,Participants are required to fast from all food and fluids from midnight (00:00)
Experimental Dietary Supplement,Active Comparator No treatment
Preoperative oral carbohydrate loading with apple juice,Overnight fasting

Sponsors

Chaloem Phrakiat Rayong Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Singleton pregnancy 2. Term pregnancy with gestational age 37 weeks or more 3. Scheduled for elective cesarean section 4. Undergoing spinal anesthesia 5. ASA physical status I to II 6. Able to communicate and assess the Visual Analog Scale VAS 7. Willing to participate and provide written informed consent

Exclusion criteria

Exclusion criteria: 1. Active labor 2. History of psychiatric disorders affecting anxiety assessment, such as anxiety disorder or panic disorder 3. Conditions affecting gastric emptying, including pregestational diabetes mellitus, gestational diabetes mellitus, or symptomatic gastroesophageal reflux disease 4. Body mass index 40 kg/m2 or more 5. Contraindications to spinal anesthesia, including coagulopathy, thrombocytopenia, local infection at needle site, or raised intracranial pressure 6. History of allergy to apple juice or fructose 7. Severe obstetric complications, including severe preeclampsia, eclampsia, or placenta accreta spectrum with anticipated massive hemorrhage 8. Major intraoperative complications, including postpartum hemorrhage with estimated blood loss 1,000 mL or more, bowel injury, or bladder injury 9. Use of opioid analgesics before surgery 10. Conversion from spinal anesthesia to general anesthesia during surgery 11. Inability to comply with fasting or apple juice protocol 12. Refusal or withdrawal of informed consent during the study

Design outcomes

Primary

MeasureTime frame
Preoperative anxiety Upon arrival in the operative room, approximately 30 minutes before surgery Visual analog scale 0-10: 0 defined no anxiety and 10 defined worst anxiety

Secondary

MeasureTime frame
Hunger Upon arrival in the operative room, approximately 30 minutes before surgery Visual analog scale 0-10: 0 defined no hunger and 10 defined worst hunger,Thirst Upon arrival in the operative room, approximately 30 minutes before surgery Visual analog scale: 0-10: 0 defined no thirst and 10 defined worst thirst,Intraoperative nausea/vomiting During intraoperative period Direct observation by anesthesia nurse,Time to first flatus Time from end of surgery to first passage of flatus Self-report by patient,Patient satisfaction Prior to discharge Visual analog scale 0-10: 0 defined worst satisfaction and 10 defined best satisfaction

Countries

Thailand

Contacts

Public ContactPasu Tuangjarwinai

Chaloem Phrakiat Rayong Hospital

nowpasu@gmail.com038684444

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026