Digital Depression Therapy with Supportive Assistants: An Examination of the Efficacy and Mechanisms of Change of the Step-by-Step Program in Thailand

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260506003

Enrollment

160

Registered

2026-05-06

Start date

2026-03-28

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

participants with mild depression symptoms (9Q, 7 to 12) engaged in self-guided learning, while those with moderate depression symptoms (9Q, 13 to 18) received guided self-help through e-helpers. depression, digital mental health, task-shifting, Step-by-Step, cultural adaptation

Interventions

A culturally adapted Thai version of the WHO&#039

s Step-by-Step (SbS), a digital self-help program comprising five sessions grounded in Behavioral Activation (BA). ,It is a control group that does not receive the intervention/treatment in the initia

Experimental Behavioral,No Intervention No treatment

a digital self-help program comprising five sessions grounded in Behavioral Activation,Waiting-list group

Eligibility

Sex/Gender

All

Age

15 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1.Aged 15-35 years (based on the group that responded best in the pilot study). 2.Have a depression screening score (9Q) of 7 or higher (mild to moderate level). 3. Able to access the internet and use a smartphone or computer, and provide informed consent to participate in the research. 4.Participants under 18 years old must obtain parental consent.

Exclusion criteria

Exclusion criteria: 1. At high risk of suicide (assessed from 9Q item 9 or 8Q) 2. Has a history of severe psychiatric diagnoses including psychosis, mania (bipolar disorder), or dementia. 3. They are currently receiving other intensive forms of psychotherapy at the same time.

Design outcomes

Primary

Measure	Time frame
Depression before, after intervention, at 3 months after intervention 9Q Assessment Scale,risk of suicide before, after intervention, at 3 months after intervention 8Q Assessment Scale	—

Secondary

Measure	Time frame
Quality of Life before, after intervention, at 3 months after intervention SF-12,General Anxiety Disorder before, after intervention, at 3 months after intervention GAD-7	—

Countries

Thailand

Contacts

Public ContactKedsaraporn Kenbubpha

Boromarajonani College of Nursing Sunpasitthiprasong, Faculty of Nursing, Praboromarajchanok Institute, Thailand

kedsaraporn@bcnsp.ac.th045255462

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026