adults aged 18 to 50 years with mild acne vulgaris acne vulgaris, treatment, diet, intermittent fasting, time restricted feeding
Conditions
Interventions
Participants in the IF group followed a 16:8 TRF regimen for 8 weeks. Participants were instructed to maintain a consistent daily eating schedule throughout the study period. (Individuals fast for 16
Experimental Behavioral,No Intervention No treatment
Intermittent fasting (IF) group,non time restricted feeding (NTRF) group
Sponsors
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Male or female participants aged 18 to 50 years. 2. Presence of mild facial acne vulgaris, defined by an Investigator Global Assessment (IGA) score of 1 to 2. 3. Participants who are willing to participate in the study and provide written informed consent prior to enrollment. 4. Participants who are able to comply with study procedures and attend follow-up visits throughout the 8-week study period.
Exclusion criteria
Exclusion criteria: 1. Participants who received systemic acne treatments, including oral antibiotics or anti-androgen therapies (e.g., spironolactone, oral contraceptive pills), within 4 weeks prior to study enrollment. 2. Participants who received oral isotretinoin within 6 months prior to enrollment, or topical retinoids (e.g., tretinoin, adapalene) within 4 weeks prior to enrollment. 3.Participants who received oral corticosteroids within 8 weeks prior to enrollment, or topical corticosteroids applied to the facial area within 2 weeks prior to enrollment. 4. Participants who used topical medications, including vasoconstrictors, antibiotics, benzoyl peroxide, non steroidal anti inflammatory drugs, or azelaic acid, within 2 weeks prior to enrollment. 5. Participants who underwent facial laser treatments, including both ablative and non-ablative lasers, within 4 weeks prior to enrollment. 6. Participants currently using hormonal contraceptives, including oral, injectable, implantable, or intrauterine devices containing hormones. 7. Participants with underlying medical conditions known to affect acne severity, including polycystic ovary syndrome (PCOS). 8. Participants with a history of herpes simplex infection or active dermatitis within the past 3 months, or a history of skin cancer. 9. Participants with other facial dermatologic conditions that may interfere with accurate acne assessment, such as seborrheic dermatitis or rosacea. 10. Female participants who are planning pregnancy, currently pregnant, or breastfeeding. 11. Participants with underlying systemic diseases, including diabetes mellitus requiring pharmacologic treatment, renal disease, cardiovascular disease, or malignancy. 12. Participants who were already practicing intermittent fasting or time-restricted eating prior to enrollment. 13. Participants with a history of eating disorders. 14. Participants with a body mass index (BMI) less than 19 kg per m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acne lesion 8 weeks Acne lesion count | — |
Secondary
| Measure | Time frame |
|---|---|
| Acne severity, Skin biophysical parameter 8 weeks IGA score, Skin biophysical parameter | — |
Countries
Thailand
Contacts
Public ContactWoranidtha Tarnmaneewongse
Division of Dermatology, Department of Medicine, Faculty of Medicine, Chulalongkorn University
Outcome results
None listed