healthy healthy
Conditions
Interventions
Participants took five 300-mg tablets three times a day, 30 minutes before meals, for a duration of 7 days.
Experimental Drug
Thai herbal Sahatsatara
Sponsors
Routine to Research Unit (R2R)
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Thai participants 2. body mass index 18-24 3. Healthy following vital sign, physical examination 4. Laboratory test is accepted criteria 5. Participants provided written informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Use of medications affecting platelet function (e.g., aspirin, clopidogrel, ticlopidine). 2. History of hypersensitivity to herbs or any ingredients in the Sahas-tara formula. 3. Presence of chronic diseases requiring regular medication or a history of peptic ulcers. 4. Regular consumption or inability to abstain from tea, coffee, and caffeinated drinks during the study. 5. Regular alcohol consumption or history of drug addiction. 6. Use of dietary supplements or vitamins within 14 days prior to and during the study. 7. Consumption of food or medicine containing Sahas-tara ingredients within 14 days before the study. 8. Current smokers or those who quit less than 14 days before the study. 9. Participation in other clinical trials within the past 30 days. 10. Pregnancy, breastfeeding, use of oral contraceptives, menstruation, or positive pregnancy test. 11. Blood donation or receiving a blood transfusion within the past 90 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| platelet aggregation Day 0, 1, and 8 one-way ANOVA | — |
Secondary
| Measure | Time frame |
|---|---|
| Platelet COX-1 mRNA expression Day 0, 1, and 8 one-way ANOVA,Platelet COX-2 mRNA expression Day 0, 1, and 8 one-way ANOVA,Plasma TXB2 Day 0, 1, and 8 one-way ANOVA | — |
Countries
Thailand
Contacts
Public ContactPravit Akarasereenont
Center of applied Thai traditional medicine, Faculty of medicine Siririaj hospital
Outcome results
None listed