Comparison of Programmed Intermittent Bolus Regimens for Continuous Fascia Iliaca Compartment Block in Elderly Patients with Hip Fracture: A Randomized-Controlled Trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260502008

Enrollment

Registered

2026-05-02

Start date

2026-04-21

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Geriatric patients with hip fracture Hip Fractures Fascia Iliaca Compartment Block Peripheral Nerve Block Bupivacaine Analgesia Programmed Intermittent Bolus Pain Measurement

Interventions

Patients receive continuous fascia iliaca compartment block via catheter. After an initial bolus of 0.25% bupivacaine 30 mL, programmed intermittent bolus regimen is administered as 0.1% bupivacaine 5

Active Comparator Procedure/Surgery,Experimental Procedure/Surgery

0.1% bupivacaine, 5 mL per bolus administered over 1 minute, every 30 minutes ( Group A),0.1% bupivacaine, 20 mL per bolus administered over 4 minutes, every 2 hours (Group B)

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients age more than or equal to 65 years old with hip fractures 2.American Society of Anesthesiologists - Physical Status (ASA-PS 2-4)

Exclusion criteria

Exclusion criteria: 1.Refuse to participate 2.Allergy or contraindicated to any of study drugs 3.Inability to communicate or report pain scores. 4.Skin infection at the block site 5.BW less than 45 kg

Design outcomes

Primary

Measure	Time frame
NRS pain score on movement 24 hours after initiation of c-FICB Numeric Rating Scale (0 to 10)	—

Secondary

Measure	Time frame
NRS pain score at rest and on movement Before and 15 minutes after catheter placement, 6, 12, 18, 24, 36, and 48 hours Numeric Rating Scale (0 to 10),Total fentanyl consumption 0 to 24 hours and 24 to 48 hours after catheter placement Total dose in micrograms,Time to first analgesic request Within 48 hours after catheter placement Time in minutes,Sensory block distribution (FN and LFCN) 15 minutes, 6, 12, 18, 24, 36, and 48 hours Cold sensation scale (0 to 2),Block-related complications During study period (up to 48 hours) Incidence (infection, dislodgement, LAST),Opioid-related adverse events Within 48 hours after catheter placement Incidence (nausea, vomiting, sedation, respiratory depression)	—

Measure

Time frame

NRS pain score at rest and on movement Before and 15 minutes after catheter placement, 6, 12, 18, 24, 36, and 48 hours Numeric Rating Scale (0 to 10),Total fentanyl consumption 0 to 24 hours and 24 to 48 hours after catheter placement Total dose in micrograms,Time to first analgesic request Within 48 hours after catheter placement Time in minutes,Sensory block distribution (FN and LFCN) 15 minutes, 6, 12, 18, 24, 36, and 48 hours Cold sensation scale (0 to 2),Block-related complications During study period (up to 48 hours) Incidence (infection, dislodgement, LAST),Opioid-related adverse events Within 48 hours after catheter placement Incidence (nausea, vomiting, sedation, respiratory depression)

—

Countries

Thailand

Contacts

Public ContactKanyaphak Udomsin

Faculty of Medicine, Khon Kaen University

kanyud@kku.ac.th0644460184

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026