Skip to content

COMPARISON OF INTER-APPOINTMENT PAIN REDUCTION DURING ROOT CANAL TREATMENT IN SYMPTOMATIC APICAL PERIODONTITIS BY USING CONVENTIONAL IRRIGATION AND ENDOACTIVATOR IRRIGATION SYSTEM: A RANDOMIZED CONTROLLED TRIAL

COMPARISON OF INTER-APPOINTMENT PAIN REDUCTION DURING ROOT CANAL TREATMENT IN SYMPTOMATIC APICAL PERIODONTITIS BY USING CONVENTIONAL IRRIGATION AND ENDOACTIVATOR IRRIGATION SYSTEM: A RANDOMIZED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260502006
Enrollment
306
Registered
2026-05-02
Start date
2023-12-19
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inter-appointment pain during root canal treatment in symptomatic apical periodontitis EndoActivator, Conventional irrigation, Root canal treatment, Symptomatic apical periodontitis, Inter-appointment pain.

Interventions

Root canal treatment performed using conventional syringe irrigation technique during biomechanical preparation.,Root canal treatment performed using sonic activated irrigation with EndoActivator syst
Active Comparator Device,Experimental Device
Conventional syringe irrigation,Sonic activated irrigation using EndoActivator system

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Healthy individuals between the ages of 18 and 65 years. 2. Permanent, mature, single-rooted teeth. 3. Teeth diagnosed with symptomatic apical periodontitis, as per the operational definition. 4. Patients of all genders.

Exclusion criteria

Exclusion criteria: 1. Multi-rooted teeth. 2. Teeth exhibiting internal or external resorption. 3. Patients with a known allergy to non-steroidal anti-inflammatory drugs (NSAIDs). 4. Teeth with severe periodontal disease. 5. Teeth with open apices.

Design outcomes

Primary

MeasureTime frame
Inter-appointment pain reduction 24 hours and 48 hours after treatment Percentage reduction in pain measured using Visual Analog Scale (VAS)

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Pakistan

Contacts

Public ContactNoorullah Soomro

Isra University Hospital

nsoomro@hotmail.co.uk00923358259018

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026