Effect of Adding Thai-strained Probiotics in the Standard Treatment of Bacterial Vaginosis in Non-pregnant Reproductive-aged Thai Women: A Randomized Study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260428006

Enrollment

120

Registered

2026-04-28

Start date

2026-04-16

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

reproductive-aged women with bacterial vaginosis bacterial vaginosis, metronidazole, probiotics, placebo, Amsel criteria

Interventions

Lactobacillus rhamnosus TM14 Lactobacillus reuteri TF314 Lactobacillus paracasei MSMC39-1 Bifidobacterium animalis TA1 10000000000 cfu/capsule per oral once daily 14 days ,Whey protein per oral once

Active Comparator Drug,Placebo Comparator Drug

Probiotics,Placebo

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-50 years 2.Presenting with abnormal vaginal discharge 3.Being diagnosed with bacterial vaginosis using Amsel criteria 4.Being non-pregnant

Exclusion criteria

Exclusion criteria: 1. Allergy to metronidazole, probiotics 2.Received antibiotics in two weeks prior to enrolment

Design outcomes

Primary

Measure	Time frame
cluecell Day 15-25 percentage of clue cells	—

Secondary

Measure	Time frame
Amsel Day 15-25 at least 3 of 4 Amsel criteria; clinical approach and microscope,clinical cure 1wk and 2wk Absence or presence of presenting symptoms; interview,Lactobacilli Day 0, 15-25 change from baseline being presented in Log; qPCR ,Recurrence 2 4 6 months Number of recurrent symptoms; interview	—

Countries

Thailand

Contacts

Public Contactchenchit Pichailuck

Mahidol University

chenchit.cha@mahidol.ac.th0918158080

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Jun 29, 2026