Diaphragm ultrasound for predicting non-invasive respiratory support failure in acute respiratory failure patients in ED

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20260427013

Enrollment

196

Registered

2026-04-27

Start date

2026-04-24

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adults (age over 18 years old) with acute respiratory failure from any cause. acute respiratory failure non-invasive respiratory support failure diaphragm ultrasound

Interventions

Adult patients with acute respiratory failure receiving non-invasive respiratory support

Diagnostic

Acute respiratory failure

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Acute respiratory failure patients who received non-invasive respiratory support in ER

Exclusion criteria

Exclusion criteria: 1.Pregnancy, 2.Patients with a do-not-intubate order, 3.Patients requiring immediate intubation, 4.Patients with severe hypoxemic respiratory failure (PaO2 <60 mmHg or SpO2 <90% despite receiving maximum oxygen therapy) or severe hypercapnic respiratory failure (pH <7.25), 5.Hemodynamically unstable patients or those with life-threatening arrhythmias, 6.Patients with neuromuscular diseases that may affect diaphragm function, 7.Patients with upper airway obstruction, 8.Patients with acute coronary syndrome, 9.Patients for whom diaphragm ultrasound may delay treatment, 10.Patients in whom optimal ultrasound images cannot be obtained

Design outcomes

Primary

Measure	Time frame
non-invasive respiratory support failure During hospital stay Follow the patients throughout the treatment process. Record whether treatment is escalated from high-flow nasal cannula to non-invasive ventilation or intubation.	—

Secondary

Measure	Time frame
Intubation rate During hospital stay Follow the patients throughout the hospital admission. Record if the patients are intubated.,In-hospital mortality During hospital stay Follow the patients throughout the hospital admission. ,Lenght of hospital stay During hospital stay Follow the patients throughout the hospital admission.	—

Countries

Thailand

Contacts

Public ContactApichaya Monsomboon

Deparment of Emergency Medicine, Faculty of Medicine Siriraj Hospital, Mahidol university

apich_ja@yahoo.com024199216

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026